Publications by authors named "Camila Cardenas-Calderon"
Several clinical issues are associated with reduced oxygen delivery to tissues due to impaired vascular perfusion; moreover, organs procured for transplantation are subjected to severe hypoxia during preservation. Consequently, alternative tissue oxygenation is an active field in biomedical research where several innovative approaches have been recently proposed. Among these, intravascular photosynthesis represents a promising approach as it relies on the intrinsic capacity of certain microorganisms to produce oxygen upon illumination.
View Article and Find Full Text PDFOxygen is essential for tissue regeneration, playing a crucial role in several processes, including cell metabolism and immune response. Therefore, the delivery of oxygen to wounds is an active field of research, and recent studies have highlighted the potential use of photosynthetic biomaterials as alternative oxygenation approach. However, while plants have traditionally been used to enhance tissue regeneration, their potential to produce and deliver local oxygen to wounds has not yet been explored.
View Article and Find Full Text PDFArticle Synopsis
- Chronic wounds struggle to heal primarily due to persistent infections from biofilms, which consist of multiple bacterial species, but the interactions between these infections and the body's response are not fully understood.
- Researchers studied the behavior of biofilms formed by Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis in collagen scaffolds to analyze their impact on wound healing both in vitro and in vivo.
- The study found that while mice survived the implantation of these scaffolds, they exhibited significant health issues, revealing complex infection patterns and immune responses in the body, which could help advance treatments for infected wounds.