Near-fatal cocaine intoxication in an infant with thrombotic microangiopathy associated with multiple organ failure.

Objective: To report a pediatric case of drug-induced thrombotic microangiopathy caused by cocaine.

Case Description: We report a nine-month-old patient who developed thrombotic microangiopathies after extreme cocaine intoxication, multiple organ dysfunction syndrome with hemodynamic dysfunction, anuric renal failure, liver failure, encephalopathy, and myocardial injury, corresponding phenotypically to thrombocytopenia-associated multiple organ failure. The patient received continuous venous hemofiltration and therapeutic plasma exchange, recovering satisfactorily.

[Extreme electrolyte depletion associated with septic shock as a form of presentation of cystic fibrosis].

Unlabelled: In the pediatric emergency department, dehydrated children are one of the most frequent causes for consultation, however, the coexistence of hyponatremia with hypochloremia and metabolic alkalosis is rare. The presence of metabolic alkalosis due to chloride depletion has been reported as a form of presentation of Cystic Fibrosis (CF).

Objective: to describe a case of cystic fibrosis of unusual presen tation in a pediatric patient.