Leucine supplementation augments insulin secretion in pancreatic islets of malnourished mice.

Objectives: We investigated the influence of leucine supplementation on insulin secretion and on some proteins related to insulin secretion in malnourished mice.

Methods: Swiss mice (aged 21 days) received isocaloric normo-17% (NP) or 6% low-protein (LP) diet for 120 days. Half of the NP and LP mice received 1.