Nature and impact of interruptions on clinical workflow of medical residents in the inpatient setting.

Background: Medical officers (trainees) in their first to third postgraduate years (PGY-1-3s) work in complex, busy environments, performing tasks that require concentration and application of learned skills. There are frequently competing demands, and being paged is among the most common.

Objective: We quantified and described the effect of interruptions that paging created on the clinical workflow of PGY-1-3s during ward duties.

Allopurinol hypersensitivity: a systematic review of all published cases, 1950-2012.

Background: Allopurinol is the primary therapy for the management of chronic gout. Utilization of allopurinol has increased in tandem with the growing prevalence of gout globally. This exposes more patients to the risk of allopurinol hypersensitivity (AH), a rare adverse reaction characterised by a spectrum of cutaneous reactions and systemic manifestations.