Publications by authors named "Cameron R Toohey"

Acute kidney injury (AKI) is a frequent finding in acutely ill and hospitalized patients arising from various etiologies. Anuric AKI, a more pronounced form of AKI in which less than 100 cc of urine is produced per day, is most frequently encountered in hospitalized, septic, and post-surgical patients, often secondary to shock or bilateral urinary tract obstruction. The development of anuric AKI in previously healthy patients after outpatient urological procedures presents a unique challenge to physicians, as many outpatient procedures require the routine perioperative administration of multiple nephrotoxic medications.

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Article Synopsis
  • Immune checkpoint inhibitors (ICIs) like pembrolizumab are gaining traction for treating cancers that don't respond to traditional chemotherapy, but they can have serious side effects, including a rare condition called pneumatosis intestinalis (PI).
  • A report describes a 50-year-old woman who experienced severe abdominal symptoms months after starting pembrolizumab, with imaging revealing extensive PI along with other complications.
  • The report discusses potential causes of ICI-induced PI and outlines how to manage patients who experience it, highlighting the need for awareness of these risks when using ICIs in cancer treatment.
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