Publications by authors named "Cameron McDonald-Hyman"
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Synopsis of recent research by authors named "Cameron McDonald-Hyman"
- Cameron McDonald-Hyman's recent research focuses on improving outcomes in graft-versus-host disease (GVHD), particularly after allogeneic hematopoietic stem cell transplantation, by utilizing regulatory T cells (Tregs) and other immunomodulatory agents.
- Key findings include the enhanced efficacy of Treg therapies through targeted infusion techniques and the identification of specific signaling pathways (such as retinoic acid) that modulate Treg function and stability in inflammatory environments.
- Additionally, McDonald-Hyman's work highlights the detrimental effects of extracellular ATP on myeloid-derived suppressor cells (MDSCs) and the potential of novel RXR agonists to mitigate GVHD while promoting anti-tumor immunity.
