Publications by authors named "Cameron Comrie"

Rationale & Objective: Nearly half of kidney transplant recipients develop allograft failure within 10 years of transplantation and experience high mortality, significant symptom burden, and complex communication challenges. These patients may benefit from palliative care, but palliative care is infrequently provided in this population. This study explores palliative care perceptions and needs among patients with poorly functioning and declining kidney allografts.

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Background & Aims: Timely prognostic communication is a critical component of care for patients with decompensated cirrhosis (DC). However, few studies have examined the association of prognostic communication with symptoms, mood, and health-related quality of life (HRQOL) in this population.

Methods: In this cross-sectional study of 218 outpatients with DC, we assessed their self-reported health status (terminally ill vs not terminally ill), their prognostic communication with their hepatologists (Prognosis and Treatment Preferences Questionnaire), symptom burden (Revised Edmonton Symptom Assessment Scale), psychological distress (Hospital Anxiety and Depression Scale), and HRQOL (Short-Form Liver Disease Quality of Life scale).

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Article Synopsis
  • - This study investigates how different sociodemographic factors and health conditions impact serum microRNA (miRNA) levels in women who do not have ovarian cancer, using data from 1,576 women from a biobank between 2012 and 2019.
  • - Significant variations in miRNA expression were linked to factors such as age, obesity, menopause, BRCA gene mutations, and medical history, while other factors like smoking and diabetes had little influence.
  • - The findings highlight the necessity to account for these confounding variables when developing clinical tests for cancer screening, improving the accuracy of miRNA biomarkers for ovarian cancer detection.
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Trauma centers demonstrate an impressive ability to save lives, as reflected by inpatient survival rates of more than 95% in the United States. Nevertheless, we fail to allocate sufficient effort and resources to ensure that survivors and their families receive the necessary care and support after leaving the trauma center. The objective of this scoping review is to systematically map the research on collaborative care models that have been put forward to improve trauma survivorship.

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Article Synopsis
  • This study investigates how race, ethnicity, and socioeconomic status affect serum miRNA profiles, which are potential biomarkers for ovarian cancer.
  • The analysis involved serum samples from 1,586 patients, showing differences in miRNA expression among various racial and ethnic groups, with significant variations observed in seven out of eight miRNAs related to ovarian cancer risk.
  • The research emphasizes the importance of acknowledging baseline differences in biomarker tests to ensure equitable clinical implementation across diverse populations.*
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Introduction: Medical students value the opportunity to learn from patients as a supplement to traditional faculty-led education; however, long-term follow-up to understand the educational impact of these experiences is lacking. We surveyed medical students who conducted non-medical virtual encounters with transplant recipients or living donors to understand the impact on students' patient care approach after 1-2 y.

Methods: Students who completed their surgery clerkship from July 2020 to September 2021 were surveyed about this nonmedical patient encounter in January 2023.

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Background: In this era of value-based healthcare, costs must be measured alongside patient outcomes to prioritize quality improvement and inform performance-based reimbursement strategies. We sought to identify drivers of costs for patients undergoing minimally invasive esophagectomy for esophageal cancer.

Methods: Patients who underwent minimally invasive esophagectomy for esophageal cancer from December 2008 to March 2020 were included.

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This manuscript highlights the risk that shelter‐in‐place instructions during COVID‐19 places on victims of domestic violence and serves as a call‐to‐action to address this crisis.

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