An Acetylenic Lipid from the New Zealand Ascidian : Exemplification of an Improved Workflow for Determination of Absolute Configuration of Long-Chain 2-Amino-3-alkanols.

An acetylenic 2-amino-3-alcohol, distaminolyne B (), isolated from the New Zealand ascidian , is reported. The isolation and structure elucidation of and assignment of 2,3 absolute configuration (AC) using the exciton coupled circular dichroism technique are described. Using a methodologically facile workflow, the same AC was also established by analysis of specific rotation, terminal methyl C-1 δ chemical shift, and NH δ and values of the ,-diacetate derivative.