Diagnostic study of human papillomavirus DNA detection in cervical and vaginal samples using the filter paper card.

Objective: To determine the accuracy of high-risk human papillomavirus (HPV) DNA samples on filter paper in comparison to specimen transport medium (STM).

Methods: This was a cross-sectional diagnostic study of 42 consecutive women who were prospectively recruited. Each had self-collected vaginal samples on filter paper, physician-collected cervical samples on filter paper, and physician-collected cervical samples in STM.

Versatile performance edges of HBsAg Next assay in diagnosis and therapeutic monitoring of HBV infection.

Background: HBsAg Next assay (HBsAgNx) claims improved detection of HBsAg. The aim was to investigate its performance in ascertaining HBsAg loss, ability to detect HBsAg in various phases of HBV infection, specificity and its amenability to in-house neutralization.

Methods: Analytical sensitivity was investigated using NIBSC standard (3rd WHO-IS).