Publications by authors named "Calicut Kini Rao Anuradha"
Article Synopsis
- Cutaneous wound healing involves complex biological processes, with dermal fibroblasts and keratinocytes playing crucial roles in reepithelialization, but pathogenic bacteria like Pseudomonas aeruginosa can hinder this process.
- Research on three virulent strains of P. aeruginosa showed that proteins pseudolysin and protease IV negatively affect fibroblasts, keratinocytes, and endothelial cells, impairing their migration, survival, and the ability to form new blood vessels.
- Pseudolysin and protease IV also induced prolonged inflammation and delayed wound healing in mouse models, suggesting they could be targeted for improved wound management in clinical settings.
