Publications by authors named "Caleb Warren"

Article Synopsis
  • GWAS have linked genetic risk to diseases, but understanding the cellular mechanisms is tough due to disease complexity.
  • We created a framework using human blood cells and various methods to uncover these cellular processes, conducting GWAS with data from 2,600 individuals and identifying 119 genomic loci related to immune responses.
  • We found a specific type of neutrophil linked to cardiometabolic diseases and developed a model predicting chronic kidney disease risk in type 2 diabetes patients, which helps advance patient stratification and biological understanding in genetic studies.
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Humor is often described as a miracle pill for marketers, yet the effects of humor on advertising, content marketing, service, and other marketing functions are wildly inconsistent. Before scholars can know whether a pun, prank, meme, or laugh will attract sales, clicks, or five-star reviews, they need to understand why the effects of humor appear to vary. Humor has different effects because scholars have treated humor as different constructs while studying how it influences different marketing outcomes with different types of stimuli in different of situations on different types of people.

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Purpose: To evaluate if nudges delivered by text message prior to an upcoming primary care visit can increase influenza vaccination rates.

Design: Randomized, controlled trial.

Setting: Two health systems in the Northeastern US between September 2020 and March 2021.

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Encouraging vaccination is a pressing policy problem. To assess whether text-based reminders can encourage pharmacy vaccination and what kinds of messages work best, we conducted a megastudy. We randomly assigned 689,693 Walmart pharmacy patients to receive one of 22 different text reminders using a variety of different behavioral science principles to nudge flu vaccination or to a business-as-usual control condition that received no messages.

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Many Americans fail to get life-saving vaccines each year, and the availability of a vaccine for COVID-19 makes the challenge of encouraging vaccination more urgent than ever. We present a large field experiment ( = 47,306) testing 19 nudges delivered to patients via text message and designed to boost adoption of the influenza vaccine. Our findings suggest that text messages sent prior to a primary care visit can boost vaccination rates by an average of 5%.

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Despite the broad importance of humor, psychologists do not agree on the basic elements that cause people to experience laughter, amusement, and the perception that something is funny. There are more than 20 distinct psychological theories that propose appraisals that characterize humor appreciation. Most of these theories leverage a subset of five potential antecedents of humor appreciation: surprise, simultaneity, superiority, a violation appraisal, and conditions that facilitate a benign appraisal.

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After 2.5 millennia of philosophical deliberation and psychological experimentation, most scholars have concluded that humor arises from incongruity. We highlight 2 limitations of incongruity theories of humor.

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Humor is ubiquitous and often beneficial, but the conditions that elicit it have been debated for millennia. We examine two factors that jointly influence perceptions of humor: the degree to which a stimulus is a violation (tragedy vs. mishap) and one's perceived distance from the stimulus (far vs.

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Extensive research in the values and preferences literature suggests that preferences are sensitive to context and calculated at the time of choice. This has led to the view that preferences are constructed. Recent work calls for a better understanding of when preferences are constructed and when they are not.

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Humor is an important, ubiquitous phenomenon; however, seemingly disparate conditions seem to facilitate humor. We integrate these conditions by suggesting that laughter and amusement result from violations that are simultaneously seen as benign. We investigated three conditions that make a violation benign and thus humorous: (a) the presence of an alternative norm suggesting that the situation is acceptable, (b) weak commitment to the violated norm, and (c) psychological distance from the violation.

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