Publications by authors named "Caleb W Huang"
Article Synopsis
- Iliacus muscle abscess is a rare but severe condition that can initially present with vague symptoms, making diagnosis difficult.
- A 21-year-old female, who had a mechanical fall, showed symptoms resembling a respiratory infection and musculoskeletal injury, but high CRP levels led to the discovery of an iliopsoas abscess through a CT scan.
- This case underscores the need to consider iliopsoas abscess in young patients, especially when inflammatory markers are elevated, allowing for timely imaging and treatment.
Introduction: Health literacy plays an essential role in one's ability to acquire and understand critical medical information in the coronavirus disease 2019 (COVID-19) infodemic and in other pandemics. We aimed to summarise the assessment, levels and determinants of pandemic-related health literacy and its associated clinical outcomes.
Methods: A systematic review was performed in Medline, Embase, PsycINFO, CINAHL and four major preprint servers.
Background: Anxiety is associated with poor health outcomes among chronic kidney disease (CKD) patients. This review summarizes the prevalence and risk factors associated with elevated anxiety symptoms and disorders among CKD patients.
Methods: Articles evaluating the prevalence and risk factors associated with elevated anxiety symptoms and disorders among CKD patients, as diagnosed via DSM 4th or 5th edition criteria, clinical interviews or validated questionnaires, were searched in Medline®, Embase®, PsychINFO® and CINAHL®.
Exogenous hydrogen sulfide (HS) is known to exert anti-inflammatory effects both in macrophages and in animal models. In this study, we first showed that NaHS caused a concentration dependent reduction in TNFα and IL-6 secretion in LPS-stimulated RAW264.7 macrophages in the absence of cell death.
View Article and Find Full Text PDFHydrogen sulfide (H2S) is a biologically active gas that is synthesized naturally by three enzymes, cystathionine γ-lyase (CSE), cystathionine β-synthetase (CBS) and 3-mercaptopyruvate sulfurtransferase (3-MST). These enzymes are constitutively present in a wide array of biological cells and tissues and their expression can be induced by a number of disease states. It is becoming increasingly clear that H2S is an important mediator of a wide range of cell functions in health and in disease.
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- The study aims to improve cancer immunotherapy by testing whether combining TLR agonists with chemotherapy can make tumor cells more recognizable to the immune system.
- Treatment with the TLR1/2 agonist Pam3CSK4 alongside chemotherapy agent Ara-C increased the survival of mice and boosted the tumor-fighting effects compared to using either treatment alone.
- The findings suggest that this combination enhances the expression of immune-related molecules in B-cell lymphoma cells, thus improving their immunogenicity and reliance on immune cells for tumor rejection.
Mechanisms of spontaneous tumor regression have been difficult to characterize in a systematic manner due to their rare occurrence and the lack of model systems. Here, we provide evidence that early-stage B cells in Eμ-myc mice are tumorigenic and sharply regress in the periphery between 41 and 65 days of age. Regression depended on CD4(+), CD8(+), NK1.
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