Publications by authors named "Cakici E"

Background: Patients diagnosed with congenital kidney malformations are at an increased risk of developing hypertension, proteinuria, and progressing to chronic kidney disease (CKD). The present study aimed to determine the frequency of masked hypertension and ambulatory arterial stiffness index (AASI) in patients with congenital kidney malformations.

Methods: The study included 174 patients with congenital kidney malformations (48 patients with unilateral renal agenesis (URA), 40 patients with ectopic kidney (EK), 36 patients with horseshoe kidney (HK), 31 patients with multicystic dysplastic kidney (MCDK), 19 patients with unilateral renal hypoplasia (URH), and 45 healthy controls.

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Introduction: Serious outbreaks of Shiga toxin-producing Escherichia coli-associated hemolytic uremic syndrome (STEC-HUS) have been reported globally. In 2011, Germany experienced a significant outbreak of HUS caused by enteroaggregative E. coli (EAEC) O104:H4 strain.

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Aim: This meta-analysis aimed to compare the antibacterial efficacy of chitosan/chitosan nanoparticles (Ch/Ch-NPs) versus sodium hypochlorite/chlorhexidine (NaOCl/CHX).

Materials And Methods: A search was performed in four electronic databases until December 08, 2023. Studies with missing, unclear, and insufficient data sets were excluded.

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Background: Coronavirus disease 2019 (COVID-19) has been recognised as a risk factor for acute kidney injury (AKI). Our aim was to investigate the risk factors contributing to hospitalised and outpatient paediatric COVID-19-associated AKI.

Methods: A retrospective observational study was conducted on patients aged 1 month to 18 years with diagnosed COVID-19-associated AKI applied to a tertiary paediatric referral hospital between March 1, 2020 and March 1, 2022.

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Article Synopsis
  • Immunoglobulin A vasculitis with nephritis (IgAVN) is the most common vasculitis in children, and this study aimed to analyze clinical outcomes, treatments, and risk factors in a large cohort of 1148 children diagnosed with the condition.
  • The retrospective analysis revealed that poorer outcomes were associated with factors like older age, lower kidney function at onset, hypertension, and certain kidney damage features, but no specific treatment was found to be more effective than others.
  • The study concluded that there is a need for further research and clinical trials to determine effective treatments and improve health outcomes for children with IgAVN.
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The purpose of this systematic review of meta-analysis was to compare the effectiveness of removing the smearing layer using EDTA versus Chitosan (Ch) and Chitosan nanoparticles (Ch-NPs). A search was performed in four electronic databases (Web of Science, PubMed, Scopus, and Cochrane). The included studies were assessed by two reviewers using Joanna Briggs Institute's critical appraisal checklist for the quasi-experimental studies.

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Article Synopsis
  • - Crush syndrome (CS) affects 2-5% of earthquake-related injuries, leading to rhabdomyolysis and potential acute kidney injury (AKI) in about 1.5% of cases; this study focused on pediatric patients with CS who developed AKI.
  • - Researchers analyzed pediatric patients requiring dialysis and created a renal scoring system based on factors like eGFR, CPK levels, and the duration of pressure on muscles to predict the need for kidney replacement therapy (KRT).
  • - Findings revealed that 42.8% of 77 patients needed KRT, with renal score, CPK, and myoglobinuria being significant indicators for treatment, indicating that a scoring system can improve early intervention
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Background: Acute post-streptococcal glomerulonephritis (APSGN) is an immune-mediated inflammatory respsonse in the kidneys caused by nephritogenic strains of group A β-hemolytic streptococcus (GAS). The present study aimed to present a large patient cohort of APSGN patients to determine the factors that can be used for predicting the prognosis and progression to rapidly progressive glomerulonephritis (RPGN).

Methods: The study included 153 children with APSGN that were seen between January 2010 and January 2022.

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Introduction: A high vesicoureteral reflux (VUR) grade is among the specific risk factors for febrile urinary tract infection (febrile UTI) and renal scarring. The aim of this study was to examine the predictive value of some potential hematological parameters for high-grade VUR and renal scarring in children 2 to 24 months old with febrile UTI.

Methods: We retrospectively examined the clinical features, laboratory tests, and imaging studies of 163 children 2 to 24 months old with a diagnosis of febrile UTI.

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Aim: The most serious form of urinary tract infection (UTI) is acute pyelonephritis (APN), which can result in bacteremia and renal scarring. This study aims to show the roles that the systemic immune-inflammation index (SII) and the immature granulocyte (IG) percentage play in predicting APN in pediatric patients by comparing them with traditional infection markers. By illustrating a significant relationship between APN, the IG percentage, and the SII, the study's contributions to the differential diagnosis of UTI can promote a rapid and appropriate treatment of APN.

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Background: The most well-known and common long-term complication in children with renal parenchymal scarring (RPS) is hypertension (HT). The present study aimed to evaluate the presence of HT in children with RPS based on ambulatory blood pressure monitoring (ABPM) and to compare the patients' blood pressure (BP) to that in healthy controls matched for age, gender, and BMI.

Methods: The study included 55 patients aged < 18 years diagnosed with RPS who were followed up for ≥ 1 year and 48 healthy controls matched for age, gender, and BMI.

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Background: A combination of antibiotics, including metronidazole (MET), ciprofloxacin (CIP), and minocycline (MINO), has been demonstrated to disinfect bacteria in necrotic teeth before regenerative processes. It has been presented clinically that antibiotic pastes may drive to possible stem cell death, creating difficulties in removing from the canal system, which can limit the regenerative procedure. This study was designed to (1) synthesize nanofibrous webs containing various concentrations of different medicaments (triple, double, and calcium hydroxide, Ca(OH)), and (2) coat the electrospun fibrous gutta-percha (GP) cones.

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Article Synopsis
  • Immunoglobulin A (IgA) vasculitis is the most common small vessel vasculitis in children, and its long-term prognosis is notably affected by renal involvement.
  • A study of 178 pediatric patients found that 13.5% experienced renal issues, with abnormal urine tests in the first month being strong indicators for predicting these problems six months after diagnosis.
  • Key risk factors for renal involvement included older age, presence of blood or protein in urine during the first month, and the season of onset, emphasizing the importance of early urine examinations for monitoring.
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Henoch-Schönlein purpura (HSP) is the most common childhood systemic vasculitis. The present study aims to investigate the effectiveness of the immature granulocyte (IG) percentage as a new marker for predicting internal organ involvement in HSP. This study included 75 patients below 18 years old who were diagnosed with HSP.

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Objective: This study aimed to investigate the relationship between the somatization level and dyadic adjustment, gratitude, forgiveness, and perfectionism in patients with psychosomatic dermatologic complaints.

Methods: In this correlational survey study, participants were recruited using the purposive sampling method from patients with psychosomatic dermatologic complaints, who were 18 or older, married, and living in the Turkish Republic of Northern Cyprus. Data were collected from patients diagnosed as having a dermatological disease with probable psychological etiology by a dermatologist at the dermatology outpatient unit of Nicosia Dr.

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Objective: The aim of this study was to investigate the effect of photobiomodulation therapy (PBMT) on postoperative pain provoked by thermal stimulation in direct pulp capping (DPC).

Subjects And Methods: A retrospective study was performed using the records of patients who received DPC using mineral trioxide aggregate. Teeth irradiated with a laser were assigned as the PBMT group, and nonirradiated teeth were considered as the control group.

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Objective: Posttraumatic growth (PTG), defined as a positive change after a traumatic event, has become the subject of various studies, and its relationship with posttraumatic stress symptoms (PTSS) has been extensively investigated. However, studies have indicated differences in the relationship between PTG and PTSS. Therefore, this study aimed to investigate the mediating role of PTSS in the relationship between the number of traumatic losses and PTG among the 2011 Van earthquake survivors.

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Background: Children born with unilateral renal agenesis (URA) are thought to have a risk of developing hypertension, proteinuria, and progressive chronic kidney disease (CKD). The present study aimed to evaluate the long-term prognosis and clinical characteristics of children with URA.

Methods: The study included 171 patients aged < 18 years diagnosed as URA who were followed-up for ≥ 1 year and 121 healthy controls matched for age, gender, and BMI.

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: The aim of this study was to determine the demographic, clinical, treatment, and outcome features of pediatric noninfectious uveitis patients at a Turkish tertiary center.: This retrospective cohort study included 101 pediatric patients with noninfectious uveitis. Location of uveitis, laterality, age at onset of uveitis, complications of uveitis, duration of follow-up, associated systemic diseases, laboratory findings, medications used, and status of uveitis at the time of data collection were obtained from the patients' files.

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In this study, the prevalence of gambling behaviors among the North Cyprus (NC) in 2018 is compared with the data of 2007, 2012, 2014 and the relationship between acculturation and problem and pathological gambling (PPG) is examined. The population of the study consists of Turkish-speaking individuals between 18 and 65 years of age living in NC. 799 people were consequently selected according to gender, age and geographical region with a multi-stage stratified (randomized) quota.

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Objective: The current research investigated attachment styles, psychological wellbeing, and academic development among children in transnational family arrangements in Zimbabwe.

Methods: Purposive sampling was employed to select 57 children in transnational family arrangements and 41 children in conventional two-parent households aged between 8 and 14 years. Attachment Style Classification Questionnaire for latency-age children, Stirling Children's Well-being Scale, Strengths and Difficulties Questionnaire, and Questionnaire for Evaluation of Development and Behavior were applied.

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Article Synopsis
  • Acute tubulointerstitial nephritis (ATIN) is a rare but serious cause of acute kidney injury in children, with a study of 38 patients revealing that most presented symptoms included abdominal pain and nausea/vomiting.
  • The study found that a significant portion of these cases were linked to drug use, particularly non-steroidal anti-inflammatory drugs, with some patients receiving steroid treatment for severe cases.
  • Although no clear advantage of steroid therapy for overall renal recovery was noted, it may still be beneficial for faster improvement in kidney function in severe cases of ATIN.
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Background: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatologic disease of childhood. The various subtypes of JIA differ in clinical features and treatments. The aim of this study was to analyze the frequency of JIA subtypes, patient demographic and clinical features, as well as the rates of macrophage activation syndrome, uveitis, and remission in Turkish JIA patients treated at a single center, and to compare the findings to those in the literature.

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The aim of this study was to compare the clinical features of patients with elevated blood pressure and to detect variables associated with the diagnosis of primary hypertension. We identified 383 (69%) hypertensive children (197 [51.5%] with primary hypertension, and 186 [48.

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Dent disease is a rare X-linked recessive tubular disorder, characterized by the triad of low molecular-weight proteinuria, hypercalciuria, nephrocalcinosis and/or nephrolithiasis. It is caused by mutations in the gene or gene. Thirty to 80% of affected males develop end-stage kidney disease between the ages of 30 and 50 years.

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