Study of flexural strength of concrete containing mineral admixtures based on machine learning.

In this paper, the prediction of flexural strength was investigated using machine learning methods for concrete containing supplementary cementitious materials such as silica fume. First, based on a database of suitable characteristic parameters, the flexural strength prediction was carried out using linear (LR) model, random forest (RF) model, and extreme gradient boosting (XGB) model. Subsequently, the influence of each input parameter on the flexural strength was analyzed using the SHAP model based on the optimal prediction model.

[Role of TGF-β/Smad signaling pathway in diabetic kidney disease and research progress of traditional Chinese medicine intervention].

Diabetic kidney disease is an important microvascular complication of diabetes and the leading cause of end-stage renal disease. Its pathological characteristics mainly include epithelial mesenchymal transition(EMT) in glomerulus, podocyte apoptosis and autophagy, and damage of glomerular filtration barrier. Transforming growth factor-β(TGF-β)/Smad signaling pathway is specifically regulated by a variety of mechanisms, and is a classic pathway involved in physiological activities such as apoptosis, proliferation and differentiation.

[Sdudy on effect of tripterygium on plasma IL-18 content in patients with lupus nephritis].

Objective: It is to study the effect of tripterygium (TW) on the plasma IL-18 content in patients with lupus nephritis (LN) and its treatment value.

Method: The patients with LN treated with prednisone were divided into active groupand inactive group with active index. The active group was given tripterygium additionally.

[Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood].

Objective: To study the clinical effects of integrative Chinese and Western medicine in treating chronic urticaria and its impact on peripheral blood content of interleukin-10 (IL-10) and IL-8.

Methods: Patients were assigned to the treatment group and the control group according to their sequence of visiting. They were treated orally with levocetirizine hydrochloride 5 mg once a day, but additional Kangqian Decoction (a self-formulated Chinese herbal preparation consisted of thorowax root 15 g, divaricate saposhnikovia root 9 g, licorice root 15 g, moutan bark 15 g, red sage root 15 g, milkvetch root 30 g, and schisandra fruit 12 g, etc.