Discovery of three novel HLA-DPA1 alleles, HLA-DPA1*01:147N, 01:03:47, and 02:106 using next-generation sequencing.

Characterization of three novel HLA-DPA1 alleles bearing null, synonymous, and non-synonymous mutations.

Identification of four novel HLA-DQ alleles, HLA-DQA1*01:106, -DQA1*01:107, -DQA1*05:74 and -DQB1*05:01:48.

Characterization of new alleles, three HLA-DQA1 and one HLA-DQB1, bearing non-synonymous and synonymous mutations, respectively.

Identification of a novel allele with a frameshift mutation, HLA-DRB4*01:165N, using next-generation sequencing.

HLA-DRB4*01:165N exhibits deletion of a nucleotide in exon 3, producing a premature stop codon.

Next-generation sequencing identifies two novel HLA class II alleles, HLA-DRB1*01:115 and HLA-DRB1*14:224.

We identified two novel HLA class II alleles by NGS, HLA-DRB1*01:115 and HLA-DRB1*14:224.

The novel HLA class II allele, DPB1*1284:01, identified using next-generation sequencing.

Our laboratory has identified DPB1*1284:01 as a novel HLA Class II allele by NGS.