It's time to look more closely at RYR3.

study shows that ryanodine receptor 3 is important for extraocular muscle function.

CFTR gets together.

study shows that pro-secretory agonists prompt CFTR to assemble into large lipid platforms.

Small calcium leaks, big muscle adaptations.

study finds that mild calcium leak is associated with improved resistance to muscle fatigue.

Rhomboids make do with a weak hydrogen bond.

paper explores the strength of the hydrogen bond network at the active site of GlpG.

Investigating an epileptogenic mutation.

study examines how a mutation in KCNQ3 affects channel behavior.

How a mutation undermines cardiac function.

paper explores how a mutated troponin T causes cardiac hypertrophy.

Probing insulin secretion with a new tool.

study explains how chromomycin A affects insulin secretion.

Nebulin no longer nebulous.

study probes how nebulin affects muscle function.

Predicting voltage sensing.

New method predicts the molecular basis of membrane proteins' voltage sensitivity.

Propofol's paradox, explained.

Tandem studies investigate how propofol affects voltage-gated sodium channels.

Bridging the gap toward understanding short-term synaptic plasticity.

study explores a new way to conceptualize an enduring neuronal mystery.

Claudins get a closer look.

study examines claudin-15 ion selectivity and permeation.

A new model struts its stuff.

paper presents a model for studying cyclic nucleotide-modulated channels.

Deafness-associated mutation opens the gate to understanding.

New JGP study uncovers a connection between Connexin 26 fast and slow gates.

Clearing the way for synaptic vesicle release.

study shows that endocytosis aids synaptic vesicle release at ribbon synapses.

Another way of seeing things.

JGP study explores a novel photoreception pathway in a marine mollusk.

Up all night: BK channels' circadian dance with different calcium sources.

JGP study explores diurnal changes in calcium sources governing BK activity in the SCN.

Uncorking AMPA receptors.

New JGP study explains how auxiliary proteins relieve polyamine block of AMPARs.

A new model for an old friend.

JGP study suggests the anion exchanger AE1 operates via an elevator-like mechanism.

A symporter's secrets shown.

New JGP study explores the thermodynamic cycle and cation preference of the sugar symporter MelB.

Modeling pacemaker deterioration with age.

New JGP study models how sinoatrial node pacemaker activity changes in aged hearts.

Different strokes for different synaptotagmins.

JGP study shows how synaptotagmins 1 and 7 affect chromaffin cell granule fusion.

Many parts make a whole: Calcium transients sum for slow waves.

New JGP study shows how calcium events drive long intestinal slow wave plateaus.

TRPV4 in the battle of the sexes.

New JGP paper explains sexual dimorphism and tissue-specific activity of TRPV4.

Pseudomonas doesn't mind a dunking.

A new study explains 's strong resistance to osmotic down-shock.