Publications by authors named "Caitlin L Soto"
Article Synopsis
- This study discusses the treatment of a 42-year-old woman with meningitis caused by carbapenem-resistant Acinetobacter baumannii, who struggled for 13 days with persistent positive cerebrospinal fluid cultures despite receiving several antibiotics.
- After transitioning to a new treatment regimen of sulbactam-durlobactam and meropenem, her infection was finally cured, highlighting the importance of effective antibiotic selection in resistant infections.
- The research identified specific genetic markers associated with the bacteria’s resistance to cefiderocol, underscoring the complexities involved in treating CRAB infections and the need for careful monitoring of antibiotic susceptibility.
In a propensity-score-weighted cohort of 183 adults with carbapenem-resistant Enterobacterales bacteremia at 24 US hospitals, patients receiving short courses of active therapy (7-10 days, median 9 days) experienced similar odds of recurrent bacteremia or death within 30 days as those receiving prolonged courses of active therapy (14-21 days, median 14 days).
View Article and Find Full Text PDFDuration of antibiotics through care transitions: A quality improvement initiative.
Am J Infect Control
April 2023
Antibiotic resistance is increasing worldwide and can be largely attributed to excess antibiotic use. At our institution, 75% of patients were prescribed excess antibiotic days and total duration of therapy was appropriate in only 24.5% of cases per the reviewers.
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