Publications by authors named "Caitlin Aldridge"
Breast tissue density (BTD) is known to increase the risk of breast cancer but is not routinely used in the risk assessment of the population-based High-Risk Ontario Breast Screening Program (HROBSP). This prospective, IRB-approved study assessed the feasibility and impact of incorporating breast tissue density (BTD) into the risk assessment of women referred to HROBSP who were not genetic mutation carriers. All consecutive women aged 40-69 years who met criteria for HROBSP assessment and referred to Genetics from 1 December 2020 to 31 July 2021 had their lifetime risk calculated with and without BTD using Tyrer-Cuzick model version 8 (IBISv8) to gauge overall impact.
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- Genome-wide sequencing (GWS) in neonatal intensive care units provides valuable insights for parents, particularly in understanding their child's condition, but parental experiences with its outcomes are less studied.
- In a qualitative study involving interviews with 14 parents, six key themes emerged: overall positive perception of GWS, relief upon receiving results, the impact of a diagnosis on future planning and support networks, discomfort with genetic diagnoses, and low decisional regret following results.
- The findings underscore the importance of genetic counselors in assisting families to comprehend and adapt to GWS outcomes within the NICU setting.