Publications by authors named "Caitlen Stobbe"
Cell Stem Cell
September 2023
Article Synopsis
- Recent advancements in creating human blastoids from naive pluripotent stem cells have improved the efficiency and quantity of these models for studying early human development and implantation.
- The new protocol allowed researchers to conduct proteomics analysis, revealing specific phosphosite signatures important for the signaling processes in human blastoids.
- Additionally, findings indicated that endometrial stromal cells support trophoblast cell survival and growth, while single-cell RNA sequencing helped identify similarities in gene expression between blastoids and blastocysts.
