Publications by authors named "Cairui Lv"
Article Synopsis
- Macroautophagy is a process where cells recycle parts to survive stress or can lead to cell death.
- Ferroptosis is a type of cell death that doesn’t depend on autophagy but recent studies show they are connected.
- Researchers found that a protein called USP13 helps increase another protein, NFE2L2, and targeting USP13 can switch the process from autophagy to ferroptosis, which may help treat certain types of lung cancer.
Various forms of programmed cell death (PCD) exhibit distinct characteristics depending on their specific molecular mechanisms, and there are interactions among these different forms. Ferroptosis, which is related to autophagy and apoptosis, has an unknown potential interaction with pyroptosis. This study revealed a mutually antagonistic relationship between ferroptosis and pyroptosis, with 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) playing a key role in their interaction.
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Signal Transduct Target Ther
May 2022