TSFF-Net: A deep fake video detection model based on two-stream feature domain fusion.

With the advancement of deep forgery techniques, particularly propelled by generative adversarial networks (GANs), identifying deepfake faces has become increasingly challenging. Although existing forgery detection methods can identify tampering details within manipulated images, their effectiveness significantly diminishes in complex scenes, especially in low-quality images subjected to compression. To address this issue, we proposed a novel deep face forgery video detection model named Two-Stream Feature Domain Fusion Network (TSFF-Net).

Construction of Flexible Deterministic Sparse Measurement Matrix in Compressed Sensing Using Legendre Sequences.

Compressed sensing (CS) is an innovative signal acquisition and reconstruction technology that has broken through the limit of the Nyquist sampling theory. It is widely employed to optimize the measurement processes in various applications. One of the core challenges of CS is the construction of a measurement matrix.

Hydrochemical assessment of groundwater utilizing statistical analysis, integrated geochemical methods, and EWQI: a case study of Laiwu region, North China.

The investigation of groundwater quality and hydrochemical assessment holds immense significance in safeguarding and ensuring the rational utilization of groundwater resources. This study utilizes groundwater sampling and testing data from the Laiwu region (LWR), encompassing both dry and wet seasons, to delve into the hydrochemical characteristics, ion sources, and overall groundwater quality. The research findings indicate that the groundwater in LWR exhibits weak alkalinity, with the dominant ions being Ca followed by Mg, Na, and K, and HCO, SO, NO, Cl, and F.

Integrated study of hydrochemistry, quality and risk to human health of groundwater in the upper reaches of the Wulong River Basin.

Groundwater, a vital source of water supply, is currently experiencing a pollution crisis that poses a significant risk to human health. To understand the hydrochemical formation mechanisms, quality and risk to human health of groundwater in the upper reaches of the Wulong River basin, 63 sets of groundwater samples were collected and analyzed. A combination of mathematical statistics, correlation analysis, Gibbs diagram, ion ratio, and cation exchange were comprehensively employed for hydrochemical analysis, and further water quality index (WQI) and human health risk assessment were conducted.

Sedimentation and transformation of heavy metals during the transport from the Yellow River estuary to the sea: Evidence from surface sediments of the Yellow River subaqueous delta.

Estuarine and coastal areas are one of the ultimate sinks for terrestrial heavy metals which play a vital role on the aquatic ecosystem. This study examined heavy metals contents and speciations in Yellow River subaqueous delta surface sediment, to characterize their sedimentation and transformation during transport from estuary to the sea. The results showed that higher concentrations were found in the seaward and the shear front affected areas.

Interventions to Improve Self-Efficacy in Colorectal Cancer Patients and/or Caregivers: A Systematic Review and Meta-Analysis.

Objective: High levels of self-efficacy (SE) in colorectal cancer (CRC) patients and/or caregivers enable patients to cope with cancer, reduce caregiver burden, and promote quality of life (QOL) in patients and caregivers alike. This review aims to (a) identify the SE theory sources covered by SE interventions or interventions, including targeting improved SE for CRC patients and/or caregivers, to guide future development of SE interventions; and (b) explore intervention effects based on SE theory through meta-analysis.

Methods: Using five electronic databases-CINAHL, Cochrane Library, Embase, PsycINFO, and PubMed-a systematic search was performed in April 2021 to identify English or Chinese literature that studied improving SE interventions for CRC patients and/or caregivers.

M1-Type, but Not M4-Type, Melanopsin Ganglion Cells Are Physiologically Tuned to the Central Circadian Clock.

Proper circadian photoentrainment is crucial for the survival of many organisms. In mammals, intrinsically photosensitive retinal ganglion cells (ipRGCs) can use the photopigment melanopsin to sense light independently from rod and cone photoreceptors and send this information to many brain nuclei such as the suprachiasmatic nucleus (SCN), the site of the central circadian pacemaker. Here, we measure ionic currents and develop mathematical models of the electrical activity of two types of ipRGCs: M1, which projects to the SCN, and M4, which does not.

The mutual impact and moderating factors of quality of life between advanced cancer patients and their family caregivers.

Purpose: Cancer and its treatment can affect quality of life (QOL) in cancer patient and family caregiver dyads. However, the factors influencing dyad QOL remain inconclusive. Our study was designed to (i) assess dyads' QOL, and examine the relationship between the QOL of cancer patients and that of their family caregivers, and (ii) investigate factors that may modify this relationship.

The Chinese version of hospital anxiety and depression scale: Psychometric properties in Chinese cancer patients and their family caregivers.

Purpose: The Hospital Anxiety and Depression Scale (HADS) acts as one of the most frequently used self-reported measures in cancer practice. The evidence for construct validity of HADS, however, remains inconclusive. The objective of this study is to evaluate the psychometric properties of the Chinese version HADS (C-HADS) in terms of construct validity, internal consistency reliability, and concurrent validity in dyads of Chinese cancer patients and their family caregivers.

Cloning of insertion site flanking sequence and construction of transfer DNA insert mutant library in Stylosanthes colletotrichum.

Stylosanthes sp. is the most important forage legume in tropical areas worldwide. Stylosanthes anthracnose, which is mainly caused by Colletotrichum gloeosporioides, is a globally severe disease in stylo production.

Enhanced photodynamic efficiency achieved via a dual-targeted strategy based on photosensitizer/micelle structure.

The applications of photodynamic therapy (PDT) are usually limited by photosensitizer's side effect and the singlet oxygen's short half-life. Herein, we demonstrate a dual-targeting (both cellular and subcellular targeting) strategy to enhance the PDT efficacy. A cationic porphyrin derivative (MitoTPP) was synthesized as the mitochondrion-targeting photosensitizer, and the dual-targeting PDT system was then fabricated by encapsulating MitoTPP into the acid-responsive and folic acid (FA)-modified polymer micelles.

Preparation of a mitochondria-targeted and NO-releasing nanoplatform and its enhanced pro-apoptotic effect on cancer cells.

The therapeutic applications of exogenous nitric oxide are usually limited by its short half-life and its vulnerability to many biological substances, thus straightforward and precise spatiotemporal control of NO delivery may be critical to its therapeutic effects. Herein, the mitochondria-targeted and photoresponsive NO-releasing nanosystem is demonstrated as a new approach for cancer treatment. The nanosystem is fabricated by covalently incorporating a NO photo-donor and a mitochondria targeting ligand onto carbon-dots; accordingly, multi-functionalities (mitochondria-targeting, light-enhanced efficient NO-releasing, and cell imaging) are achieved.

Intrinsic physiological properties of the five types of mouse ganglion-cell photoreceptors.

In the mammalian retina, some ganglion cells express the photopigment melanopsin and function as photoreceptors. Five morphological types of these intrinsically photosensitive retinal ganglion cells (ipRGCs), M1-M5, have been identified in mice. Whereas M1 specializes in non-image-forming visual functions and drives such behaviors as the pupillary light reflex and circadian photoentrainment, the other types appear to contribute to image-forming as well as non-image-forming vision.