Publications by authors named "Cailing Duan"
Article Synopsis
- Long-term use of illicit drugs disrupts the HPA axis, affecting hormone regulation and the mental and physical health of addicts.
- This study developed a sensitive method for detecting various illicit drugs and steroids in hair samples, providing a way to monitor drug exposure and health status among users.
- The method demonstrated high accuracy and reliability, successfully identifying cortisol, MAM, MDMA, and other drugs in female users, revealing higher levels in those currently using MAM compared to those in withdrawal.
Simultaneous quantitation of zidovudine, efavirenz, lopinavir and ritonavir in human hair by liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
October 2018
Nowadays, zidovudine, efavirenz, lopinavir and ritonavir are important components of the second-line antiretroviral therapeutic regimen of National Free Antiretroviral Treatment Program in China. The measurement of antiretroviral drugs in hair will facilitate for the evaluation of the long-term adherence to highly active antiretroviral therapy. Nevertheless, no study illustrated simultaneous quantitation of the four drugs in hair.
View Article and Find Full Text PDFSimultaneous determination of antiretroviral drugs in human hair with liquid chromatography-electrospray ionization-tandem mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci
April 2018
The determination of the concentrations of antiretroviral drugs in hair is believed to be an important means for the assessment of the long-term adherence to highly active antiretroviral therapy. At present, the combination of tenofovir, lamivudine and nevirapine is widely used in China. However, there was no research reporting simultaneous determination of the three drugs in hair.
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