Publications by authors named "Caileigh Pudela"

Background: Racial/ethnic survival disparities in neuroblastoma were first reported more than a decade ago. We sought to investigate if these disparities have persisted with current era therapy.

Methods: Two patient cohorts were identified in the International Neuroblastoma Risk Group Data Commons (INRGdc) (Cohort 1: diagnosed 2001-2009, n=4359; Cohort 2: diagnosed 2010-2019, n=4891).

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Article Synopsis
  • - Neuroblastoma is a diverse childhood cancer that develops from neural crest cells in the sympathetic nervous system, with outcomes ranging from spontaneous regression to aggressive forms resistant to treatments.
  • - Patient characteristics and tumor biology play a crucial role in prognosis, especially as low- and intermediate-risk patients often have better outcomes, while only about 50% of those with high-risk neuroblastoma achieve long-term survival.
  • - Recent research has identified various genetic and chromosomal factors that contribute to neuroblastoma's development, leading to new therapies aimed at improving survival rates for affected children.
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Appendicitis is the most common reason for which pediatric patients require emergent surgery. Although surgical removal of the appendix is the standard of care for appendicitis, neutropenic patients require special consideration as optimal management for these patients remains controversial. We present a case series of 3 neutropenic patients with appendicitis, all of whom were managed differently according to the circumstances unique to each case.

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Rationale And Objectives: Managing and supervising the complex imaging examinations performed for clinical research in an academic medical center can be a daunting task. Coordinating with both radiology and research staff to ensure that the necessary imaging is performed, analyzed, and delivered in accordance with the research protocol is nontrivial. The purpose of this communication is to report on the establishment of a new Human Imaging Research Office (HIRO) at our institution that provides a dedicated infrastructure to assist with these issues and improve collaborations between radiology and research staff.

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