Publications by authors named "Caijiao Guo"
Background/aims: Circular RNAs (circRNAs) are transcribed prevalently in the genome; however, their potential roles in multiple cardiovascular diseases, particularly preeclampsia (PE), are not yet well understood. This study investigated the expression profiles of circRNAs and explored circRNA-mediated pregnancy-associated plasma protein A (PAPP-A) expression as a potential biomarker for PE before 20 weeks of pregnancy.
Methods: A nested case-control two-phase screening/validation study was performed in pregnant women before 20 weeks of gestation (before clinical diagnosis) at Guangzhou Women and Children's Medical Center from 2012 to 2015.
Platelets, inflammation, and prediction of the hypertension disorders of pregnancy.
J Matern Fetal Neonatal Med
January 2012
Objective: To assess the features of the platelets (PLTs) of hypertensive disorders of pregnancy (HDP) and to determine whether they have a predictive value for the disorders during the preclinical stage.
Methods: This study included 461 HDPs and 827 normal pregnancies. Platelet counts were compared between the two groups by an independent samples t test; a Fisher's linear discriminant analysis and receiver operator characteristic curve were performed to analyze the diagnostic effects of the variables in developing HDP.