A latent class analysis of depressive symptoms among rural Chinese adolescents and their association with psychological resilience.

Numerous studies have demonstrated the heterogeneity of depressive symptoms, but few studies have focused on the heterogeneity of depressive symptoms among rural Chinese adolescents. In November to December 2022, multistage sampling was employed to administer questionnaires to 1,816 rural adolescents aged 11-19 years from six schools in Henan Province, China. Depressive symptoms were measured using the Chinese version of the Children's Depression Inventory Scale.

A Potential Anti-Glioblastoma Compound LH20 Induces Apoptosis and Arrest of Human Glioblastoma Cells via CDK4/6 Inhibition.

Glioblastoma (GBM) is a deadly brain tumor characterized by signaling dysregulation and aberrant cell cycle control. The CDK4/6-Rb axis is dysregulated in approximately 80% of all GBM cases. In this study, the anti-GBM effect of a novel pyrimidin-2-amine, LH20 was evaluated in vitro using the primary GBM cell lines U87MG and U251.

Up-and-coming anti-epileptic effect of aloesone in : Evidenced by integrating network pharmacological analysis, , and models.

is a medically valuable plant with anti-epileptic activity; however, its mechanism of action remains unknown. In this study, network pharmacological, , and experiments were carried out to explore the potential anti-epileptic components and targets of . The main active components of were identified by searching the Traditional Chinese Medicine System Pharmacology database.

Identification of similarities and differences between myeloid and lymphoid acute leukemias using a gene-gene interaction network.

Acute myeloid leukemia (AML) is a cancer that affects the myeloid line of blood cells. Acute lymphoid leukemia (ALL) is a type of leukemia that targets the lymphoid line of blood cells. As the comparison of these two types facilitates in the understanding of their molecular pathology, exploring the similarities and differences in the mechanisms of them is worthwhile.

Occupational safety training and education for needlestick injuries among nursing students in China: intervention study.

Objectives: To confirm the effect of occupational safety training and education programs (OSTEP) on needlestick injuries (NSIs) among nursing students in China.

Methods: Compare the rates and the nature of NSIs before and after OSTEP among the nursing students in China. Firstly, questionnaires were delivered to 248 randomly selected nursing students from seven training hospitals to obtain basic information concerning relevant occupational NSIs.

Needlestick injuries among nursing students in China.

Objectives: To describe and characterize the rates and the nature of needlestick injuries among nursing students in China.

Methods: A questionnaire was delivered to 248 randomly selected nursing students from seven training hospitals to obtain information relevant occupational needlestick injuries.

Results: A total of 1144 incidents of needlestick injuries were reported among the 246 nurses during the time period of internship.