Publications by authors named "Cai-yuan Song"
Objective: To explore the preventive effect of Yougui drink on femoral head necrosis in rats under micro CT.
Methods: Twenty-five SD rats were divided into steroid hormone group (group A, 10 rats ), Yougui drink group (group B,10 rats) and normal group (group C,5 rats)with random number table. Endotoxin were injected into abdominal cavity of rats in group A and B for 2 days, methylprednisolone sodium succinate were injected by gluteus for twice a week continued for 6 weeks; group B were gavaged by Yougui drink (veryday for 8 weeks; group C did not do any processing.
Chronic osteomyelitis is one of the most common disorder in clinic. In recent years due to diabetes, peripheral vascular disease and trauma induced disease increased, the prevalence rate increased. With the development of magnetic resonance imaging and CT imaging technology, it greatly improved the accuracy of clinical diagnosis of chronic osteomyclitis and ability to describe the infection characteristics, and provide a reliable basis for clinical treatment.
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- Osteoclasts are large, multinucleated cells essential for bone absorption and derived from specific stem cells, playing a crucial role in bone metabolism regulation.
- The process of osteoclast formation and maturation involves complex regulatory mechanisms, notably the OPG/RANKL/RANK system.
- Recent research has uncovered a close relationship between immune cells and osteoclasts in bone metabolism, suggesting new treatment avenues for bone diseases, although the apoptosis mechanism of osteoclasts remains poorly understood and requires further study.