Publications by authors named "Cai-Yun Yan"

Background: Diabetic nephropathy (DN), affecting half of diabetic patients and contributing significantly to end-stage kidney disease, poses a substantial medical challenge requiring dialysis or transplantation. The nuanced onset and clinical progression of kidney disease in diabetes involve consistent renal function decline and persistent albuminuria.

Aim: To investigate Tiliroside's (Til) protective effect against diabetic nephropathy (DN) in rats under diabetic conditions.

View Article and Find Full Text PDF
Article Synopsis
  • - Pulmonary sarcomatoid carcinoma (PSC) is a rare, aggressive lung cancer subtype with poor prognosis, and conventional chemotherapy is often ineffective.
  • - A 56-year-old male patient with PSC initially struggled with chemotherapy but showed significant improvement after receiving anti-angiogenic therapy (Anlotinib) and anti-PD-1 immunotherapy (Tislelizumab).
  • - After treatment adjustments due to liver injury and hepatitis C, the patient achieved clinical complete remission with continued combined therapy of Tislelizumab and Anlotinib, indicating a potential effective strategy for PSC with TP53 mutations.
View Article and Find Full Text PDF

Objectives: Previous studies of the associations between white matter hyperintensities (WMH) and chronic kidney disease (CKD) were still conflicting; therefore, our study aimed to conduct a systematic review of all of the available research on this topic and a meta-analysis of the association between WMH and CKD among observational studies.

Setting And Design: Systematic review and meta-analysis.

Outcome Measures: Severity of WMH.

View Article and Find Full Text PDF

Salt is an important excipient for Chinese medicine salt. The standardization of its quality is conducive to ensuring the quality of Chinese medicine pieces. In this paper, the processing with brine and the processing auxiliary salt were studied from three aspects: the history evolution of salt, the history evolution of processing with brine, and the modern research of processing with brine.

View Article and Find Full Text PDF
Article Synopsis
  • * Breviscapine liposomes were made using the thin film-lyophilization method, with the phase inversion temperature and coalescence kinetics being measured to analyze their properties.
  • * Results indicated a phase inversion temperature of 63°C, with breviscapine in liposomes displaying better stability and distribution than in infusion form, highlighting their potential for therapeutic use.
View Article and Find Full Text PDF