[Efficacy of Continuous Prevention of Injury Combined with Interfereuce of Pain on Enhancement of Physical Safety and Pain Control in Patients with Multiple Myeloma].

Objective: To analyze the efficacy of continuous prevention injury combined with interference of pain on enhomcement of physical safety inside and outside hospital and pain control in patients with multiple myeloma (MM).

Methods: Two hundred and thirty-three MM patients admitted in our hospital from January 2016 to December 2017 were divided into 2 group according to odd-even number of hospitalization: routine nursing group (odd number) and combined nursing group (ever number). 119 patients in routine nursing group were given routine nursing, 114 patients in combined nursing group were given combined nursing consisting of continuous prevention of injury combined with interference of pain.

[Clinical application of whole exome sequencing in monogenic hereditary disorders in critically ill newborns].

Objective: To explore the value and significance of the clinical application of whole exome sequencing (WES) in monogenic hereditary disorders in critically ill newborns.

Methods: The critically ill newborns in the neonatal intensive care unit with suspected hereditary diseases or unclear clinical diagnosis from June 2016 to December 2018 were enrolled. The whole blood samples from both newborns and parents were collected for WES.

[Levels of blood free carnitine in preterm infants with different gestational ages and birth weights].

Objective: To examine blood concentrations of free carnitine (FC) in preterm infants with different gestational ages (GA) and birth weights (BW).

Methods: A total of 3 368 preterm infants were enrolled as subjects. According to GA, they were divided into extremely preterm birth (EPTB) group (GA <28 weeks; n=39), very preterm birth (VPTB) group (28 ≤GA <32 weeks; n=405), moderately preterm birth (MPTB) group (32 ≤GA <34 weeks; n=507), and late preterm birth (LPTB) group (34 ≤GA <37 weeks; n=2 417); according to BW, they were divided into extremely low birth weight (ELBW) group (BW <1 000 g; n=36), very low birth weight (VLBW) group (1 000 g ≤BW <1 500 g; n=387), low birth weight (LBW) group (1 500 g ≤BW <2 500 g; n=1 873), and normal birth weight (NBW) group (2 500 g ≤ BW <4 000 g; n=1 072).

Starmerella anomalae f.a., sp. nov., Starmerella asiatica f.a., sp. nov., Starmerella henanensis f.a., sp. nov. and Starmerella scarabaei f.a., sp. nov., four yeast species isolated from scarab beetles.

Eleven yeast strains representing four novel species of the genus Starmerella were isolated from scarabs beetles collected in Nanyang, Henan Province, Central China. Phylogenetic analysis using combined sequences of the D1/D2 domains of the large subunit (LSU) rRNA gene and the internal transcribed spacer (ITS) regions placed all the novel species in a clade distinct from the other known species in the clade representing the members of the genus Starmerella. These novel species differed from each other or their closest known species by more than 4.