[Effect of polydatin on miR-214 expression and liver function in ApoE-/- mice].

Objective: To study the effect of polydatin on the expression level of miR-214 and liver function in atherosclerotic mice.

Methods: Forty male ApoE(-/-) mice were randomly allocated into 4 groups (n=10), namely the model group, low- and high-dose polydatin groups, and simvastin group, with 10 male C57BL/6J mice serving as the normal control group. Mouse models of atherosclerosis were established by feeding the ApoE(-/-) mice with a high-fat diet.

Variability of glomerular filtration rate estimation equations in elderly Chinese patients with chronic kidney disease.

Background: Chronic kidney disease (CKD) is recognized worldwide as a public health problem, and its prevalence increases as the population ages. However, the applicability of formulas for estimating the glomerular filtration rate (GFR) based on serum creatinine (SC) levels in elderly Chinese patients with CKD is limited.

Materials And Methods: Based on values obtained with the technetium-99m diethylenetriaminepentaacetic acid ((99m)Tc-DTPA) renal dynamic imaging method, 319 elderly Chinese patients with CKD were enrolled in this study.

[Quercetin inhibits growth and induces apoptosis of human gastric carcinoma cells].

Aim: To study the effect of quercetin on the growth and apoptosis of human gastric carcinoma cell line MGC-803.

Methods: The measurement of inhibitory rate and apoptotic index(AI) of quercetin were done by MTT assay and TUNEL assay. The positive expression rate of P53, C-myc and P16 were detected by immunocytochemical staining.