Publications by authors named "Cai-Lan Hou"

Aims: To assess the validity and internal reliability of the International Trauma Questionnaire (ITQ) among patients diagnosed with major depressive disorder (MDD) and to explore the network structure of Complex post-traumatic stress disorder (CPTSD) among MDD patients in China.

Methods: Eligible individuals were recruited from a large tertiary hospital in Guangdong Province. Trained researchers conducted in-person interviews and administered self-report questionnaires, including demographics, medical information, and psychological assessments.

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Background: Individuals with schizophrenia tend to have negative coping styles and low levels of self-esteem, but it is unclear whether coping styles and self-esteem levels are altered in people in the prodromal phase of psychosis.

Aims: The study was designed to assess the role of coping style and self-esteem in the context of different phases of schizophrenia.

Methods: Recurrent Schizophrenia (ReSch), first-episode schizophrenia patients (FEP), genetic-high risk for psychosis (GHR) patients, and healthy controls (HC) (40 per group) were subjected to in-person clinical interviews.

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Article Synopsis
  • * Among participants, 44.4% of UHR individuals developed schizophrenia over two years, with significant genetic markers identified, including neurexin-1 and various dopamine receptor genes linked to this conversion.
  • * The findings suggest that further research with larger sample sizes is necessary to better understand the genetic pathways contributing to the transition from UHR to schizophrenia.
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  • A survey in Guangdong Province, China, focused on the prevalence and factors related to insomnia symptoms among people aged 65 and older, involving 4,001 elderly participants.
  • Findings showed that 13.44% of the elderly experienced insomnia symptoms, with 11.15% classified as subthreshold insomnia and 2.28% as clinical insomnia.
  • Factors linked to insomnia included urban living, irregular diets, lower body mass index, chronic diseases, and signs of depression and anxiety, highlighting the need for targeted healthcare interventions.
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  • The text is a correction notice for a previously published article, identified by its DOI (Digital Object Identifier) 10.1007/s41105-020-00262-0.
  • It indicates that there were errors or inaccuracies in the original publication that need to be addressed.
  • The correction aims to ensure the accuracy and reliability of the information presented in the article for readers and researchers.
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Background: Mental disorders and cognitive impairment are common in older patients with arthritis. While it is recognized that mental conditions may play a role in the connection between arthritis and cognitive impairment, the precise underlying relationship remains uncertain.

Methods: The data was derived from the baseline survey of the Guangdong Mental Health Survey in South China, involving a sample of 3,764 citizens aged 65 and older.

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  • The study investigates the relationship between gene polymorphisms and expression of NRG1, DAOA, and DISC1 in individuals at ultra-high risk (UHR) for psychosis in the Chinese Han population, as prior research had not explored this demographic.
  • Researchers analyzed samples from 18 UHR individuals, their first-degree relatives, first-episode psychosis cases, and healthy controls, examining various genetic markers and mRNA levels.
  • Findings indicate that variations in the DAOA gene are linked to UHR susceptibility, and there are interactions between the NRG1, DAOA, and DISC1 genes; notably, NRG1 expression was significantly reduced in the UHR group compared to controls, suggesting its potential role as a
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The purpose of this study was to evaluate the psychometric features of the Chinese version of the developmental dimensional diagnostic interview-short version (3Di-sv). A total sample of 138 children including 79 children with autism spectrum disorder (ASD) and 59 typically developing children completed the 3Di-sv interview. The Chinese version of the 3Di-sv has a good internal consistency (0.

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Objective: To explore the patterns and correlates of insight among patients with schizophrenia in a large Chinese population.

Method: A multi-center cross-sectional study was conducted in Guangdong province, China. Patients with schizophrenia were included.

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Aims: This study aimed to explore the dyadic effects of depression and anxiety on insomnia symptoms in Chinese older adults and their caregivers living in a community setting.

Methods: Data were collected from 1,507 pairs of older adults and their caregivers who were in the Guangdong Mental Health Survey in China. The 9-item Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder module 7 (GAD-7), and Insomnia Severity Index (ISI) were used to measure depression, anxiety, and insomnia symptoms.

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Background: Lifestyle habits are vital components of the culture of mental health treatment settings. We examined the bridge connection between depressive and anxiety symptoms and lifestyles from a network perspective using a population-based study.

Methods: Face-to-face interviews were conducted with a provincially representative sample of 13,768 inhabitants from the Guangdong Sleep and Psychosomatic Health Survey based on standardized evaluation techniques.

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Background: For decades, video game-related behaviors have been investigated in different psychologic research, much of whose attention has been paid to video game addiction (VGA), while the differences between VGA and social media addiction (SMA) should have deserved more attention. In addition to detecting common risk factors of VGA, one core question is whether social inclination (individualism or collectivism) matters.

Object: The objectives of this study were to clarify the prevalence of VGA and SMA,, identify the influencing factors of VGA, and clarify the relationships between VGA and adolescents' individualism-collectivism inclination.

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Gender differences have been found in several areas of individuals at clinical-high risk for psychosis(CHR). Therefore the risk of transition to psychosis may differ between male and female CHR, but previous work has not systematically reviewed and analyzed gender differences in conversion rates.We performed a meta-analysis according to PRISMA guidelines including all studies that assessed CHR with reliable instruments and provided data on the transition from male CHR and female CHR to psychosis to understand the conversion rate conversion in male and female CHR.

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Background: Information on major depressive disorder (MDD) and subthreshold depressive symptoms (SDS) is rarely reported in south China. This study examines the prevalence rates and patterns of MDD and SDS of a large representative sample of adult residents in south China.

Methods: The Guangdong Mental Health Survey was conducted on adults (over 18 years) from September to December 2021.

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Objective: The consequences and impact of violent behavior in schizophrenia are often serious, and identification of risk factors is of great importance to achieve early identification and effective management.

Methods: This follow-up study sampled adult patients with schizophrenia in primary mental health care in a rural area of southern China, in which 491 participants completed a comprehensive questionnaire at baseline and the 2-year follow-up. Sociodemographic, clinical and psychological assessment data were collected from all participants.

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Few studies have examined the clozapine in cohort studies of Chinese patients with schizophrenia in rural primary care. The objective of this two-year cohort study was to describe the usage of clozapine and investigate and identify the demographic, clinical correlations and risk variables which affect the use of clozapine in patients with schizophrenia. A random cluster sampling technique was used, and participants were collected from China National Psychiatric Management System (CNPMS).

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Background: Mental health literacy (MHL) is rarely reported in the Chinese elderly. This study explored the pattern of MHL in the Chinese elderly in relation to depression, anxiety and poor sleep quality.

Methods: A cross-sectional study was conducted among older adults in Guangzhou, south China.

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Objective: Quality of life (QoL) has been always an important way to evaluate the outcomes of schizophrenia, but there have been few previous longitudinal studies and few in middle-income countries. This study aimed to explore the QoL in Chinese patients with schizophrenia treated in primary mental health care and the risk factors of QoL over time.

Methods: Patients with schizophrenia treated in primary mental health care in rural/regional areas in Luoding, Guangdong, PR China, were evaluated with an extended questionnaire including the Chinese version of the World Health Organization Quality of Life (WHOQOL-BREF) at baseline and 2-year follow-up.

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Background: Internet is gradually reshaping adolescents' behaviors in China. It is important to identify the prevalence and risk factors to predict Internet addiction among adolescent psychiatric patients.

Methods: The survey was conducted among inpatient or outpatient adolescent patients with mental disorders.

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