Publications by authors named "Cai Yongzhi"

Background: The thickness and motion of the Interatrial Septum (IAS) possibly serves as indicators of both structural and functional remodeling of left atrium. This study aims to use transesophageal echocardiography (TEE) to assess IAS motion in non-valvular atrial fibrillation (NVAF) and investigate its correlation with the risk of spontaneous echo contrast (SEC) and thrombus (TH).

Methods: We conducted a cross-sectional study on 318 patients with NVAF who underwent transthoracic echocardiography and TEE.

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Background: Functional tricuspid regurgitation (FTR) has a pathophysiological connection with right heart remodeling. Given the increasing focus on right atrial remodeling in recent years, a comprehensive study of all aspects of right heart remodeling is crucial for understanding the progression and treatment of FTR. In the scientific literature, there is a lack of comprehensive exploration of right atrial remodeling in patients with FTR, and no reports on the potential correlation between the degree of this remodeling and the severity of tricuspid regurgitation (TR) have been published.

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  • Mitral regurgitation (MR) is commonly found in patients with non-valvular atrial fibrillation (NVAF) and can worsen the condition; this study examines the 3D anatomy of the mitral valve (MV) in different NVAF types to understand MR's mechanisms.
  • The study analyzed 82 patients with paroxysmal AF and 66 with persistent AF via real-time 3D echocardiography, comparing them to a control group of 30 patients, measuring various heart structures and functions.
  • Results showed that persistent AF patients had larger left atrial volumes and higher MR rates, with notable changes in mitral annular shape and size compared to the control group, indicating structural changes are
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  • Catheter ablation (CA) is an effective treatment for non-valvular atrial fibrillation (NVAF), but many patients still experience AF recurrence after the procedure, prompting this study to explore predictive markers.
  • The study analyzed 380 NVAF patients who underwent CA, finding that lower left atrial (LA) function and higher LA stiffness were associated with increased recurrence of AF after a median follow-up of 9 months.
  • Key findings include that LA stiffness and LA reservoir strain (LASr) serve as independent predictors of AF recurrence, highlighting the importance of evaluating LA function to guide patient management post-ablation.
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  • The study focuses on using echocardiographic parameters to predict left atrial low-voltage areas (LA-LVAs) in patients with non-valvular atrial fibrillation (NVAF), which are important for treatment and prognosis.
  • Out of 190 patients, 42.6% showed LA-LVAs, with a higher prevalence in persistent atrial fibrillation cases; the LA-LVAs group had significant differences in age, heart rate, and echocardiographic metrics compared to the non-LVAs group.
  • The findings suggest that automatically assessed left atrial volume index (LAVi) and left atrial reservoir strain (LASr) can effectively
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  • This study investigates how hemodynamic parameters affect the recurrence of atrial fibrillation (AF) after catheter ablation, aiming to create a predictive nomogram based on these parameters for nonvalvular atrial fibrillation (NVAF) patients.
  • Researchers analyzed data from 380 NVAF patients who underwent catheter ablation, identifying 4 key predictors of AF recurrence: persistent AF, S/D ratio of pulmonary vein, left atrial acceleration factor, and left atrial appendage peak emptying flow velocity.
  • The resulting nomogram accurately predicts AF recurrence at 1 and 2 years, demonstrating its potential to help clinicians assess risk in patients undergoing catheter ablation for NVAF.
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Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with a high risk of stroke. This study was designed to investigate the relationship between hemodynamic parameters and left atrial thrombus/spontaneous echo contrast (LAT/SEC) in non-valvular atrial fibrillation (NVAF) patients and establish a predictive nomogram that integrates hemodynamic parameters with clinical predictors to predict the risk of LAT/SEC.

Methods: From January 2019 to September 2022, a total of 354 consecutive patients with NVAF were enrolled in this cross-sectional study at the First Affiliated Hospital of Guangxi Medical University.

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Background: Rheumatic mitral stenosis(RMS) may leads to left ventricular remodeling (LVR), which can persist even after valve surgery. Identifying markers for early structure and function in patients with rheumatic heart disease who are at risk for adverse LVR after surgery can help determine the optimal timing of intervention. This study aimed to investigate whether preoperative parameters of global left ventricular long-axis strain (LVGLS) and mechanical discretization (MD) could predict postoperative adverse LVR.

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Myocardial amyloidosis (CA) differs from other etiological pathologies of left ventricular hypertrophy in that transthoracic echocardiography is challenging to assess the texture features based on human visual observation. There are few studies on myocardial texture based on echocardiography. Therefore, this paper proposes an adaptive machine learning method based on ultrasonic image texture features to identify CA.

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thrombosis is a significant pathophysiological basis for the development of pulmonary hypertension (PH). However, thrombolytic therapy for thrombus in PH was often hampered by the apparent side effects and the low bioavailability of common thrombolytic medications. Nanoscale cyclic RGD (cRGD)-decorated liposomes have received much attention thanks to their thrombus-targeting and biodegradability properties.

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Purpose: To study the thrombolytic effect and safety of cRGD urokinase liposomes (cRGD-UK-LIP) in rats with acute pulmonary microthromboembolism (APMTE), and explore the application value of echocardiography (ECHO) in animal models.

Patients And Methods: Ninety-six SD rats were randomized into 6 groups (16/group): normal control, sham operation, APMTE, normal saline (NS), free urokinase (UK), cRGD-UK-LIP. Four groups (APMTE, NS, UK, cRGD-UK-LIP) of rats were injected with autologous thrombus to induce APMTE.

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