Publications by authors named "Cai Wencan"
Evaluation of the analytical performance of endocrine analytes using sigma metrics.
J Clin Lab Anal
January 2021
Background: (a) To evaluate the clinical performance of endocrine analytes using the sigma metrics (σ) model. (b) To redesign quality control strategies for performance improvement.
Methods: The sigma values of the analytes were initially evaluated based on the allowable total error (TEa), bias, and coefficient of variation (CV) at QC materials level 1 and 2 in March 2018.
Background: Detection of serum squamous cell carcinoma (SCC) antigen (SCCA) contributes to the diagnosis and therapeutic monitoring of SCC. However, the results obtained from different detection systems are not always consistent.
Methods: In this study, we compared the performance of electrochemiluminescence assays (ECLIAs) and flow fluorescence immunoassays (FFIAs) (e.
Background: As key negative regulators of gene expression, microRNAs (miRNAs) play an important role in the onset and progression of hepatocellular carcinoma (HCC). This study aimed to identify the miRNAs involved in HCC carcinogenesis and their regulated genes.
Methods: The Gene Expression Omnibus (GEO) dataset (GSE108724) was chosen and explored to identify differentially expressed miRNAs using GEO2R.
Article Synopsis
- - The study aimed to assess the effectiveness of testing serum levels of Golgi protein-73, alpha-fetoprotein-L3, and Tat-interacting protein-30 in diagnosing liver issues related to hepatitis B, specifically cirrhosis and hepatocellular carcinoma.
- - Conducted in China with 721 participants, including hepatitis B patients and healthy controls, the study found significant differences in the serum levels of the proteins among those with hepatocellular carcinoma compared to other groups.
- - Results indicated that the combined tests had good sensitivity (86.02% for cancer diagnosis) and specificity (92.51% for cancer) for identifying liver diseases, suggesting it could enhance diagnostic accuracy in clinical settings.
[Determination of oxidation-reduction level in patients with rheumatoid arthritis].
Di Yi Jun Yi Da Xue Xue Bao
June 2005
Objective: To examine the oxidation or reduction products in patients with rheumatism arthritis (RA), and investigate the relationship between oxidation or reduction products and occurrence and development of RA.
Methods: The serum levels of total ascorbic acid (TAA), dehydroascorbic acid (DHAA)/TAA, vitamin E, advanced oxidation protein products (AOPP) and malondialdehyde (MDA) were detected by high-performance liquid chromatography with electrochemical detection in 83 RA patients and 30 healthy adults. Correlation analysis of AOPP, MDA and hs-CRP was performed.