Publications by authors named "Cai Shan Wang"
Article Synopsis
- Aquaculture, or fish farming, has grown quickly, but it's causing problems for the environment, especially with water pollution from waste.
- This study looked at how different types of aquaculture (like shrimp, fish, and shellfish) affect something called dissolved organic matter (DOM), which is important for the health of water ecosystems.
- The results showed that crustacean and fish farms produce more DOM than shellfish farms, and each type has different chemical makeups that can impact the health of the water and the creatures living in it.
Article Synopsis
- - The study investigates the relationship between the substantia nigra hyperechogenicity (SN+) detected by transcranial sonography and the severity of Parkinson's disease (PD), discovering a U-shaped correlation as PD progresses through different stages.
- - A total of 612 PD patients were analyzed using the Unified Parkinson's Disease Rating Scale (UPDRS) scores, showing that in early stages (H-Y stage 1), a larger SN+ area correlated with less disease severity, while in advanced stages (H-Y stage 3 and above), a larger SN+ area correlated with greater disease severity.
- - The findings suggest that the evolution of SN+ area correlations with UPDRS scores may reflect changing pathological mechanisms related
Article Synopsis
- - This study used shear wave elastography (SWE) to measure muscle stiffness in the lower gastrocnemius of Parkinson's disease patients with postural instability gait difficulty (PIGD) and those who are tremor dominant (TD) to assess differences in muscle characteristics during rest and exercise.
- - The study included 75 PD patients and 40 healthy controls, finding that muscle stiffness was highest in healthy individuals, followed by TD patients, and lowest in those with PIGD, with certain stiffness metrics showing a correlation with disease duration and severity in PIGD patients.
- - Results suggest that SWE is a valuable tool for evaluating muscle strength and can help differentiate between PIGD and TD patients, indicating a potential
Article Synopsis
- Diclofenac (DCF) is a common medicine found in rivers and lakes, used to help reduce pain and inflammation.
- Researchers looked into how well water treatment methods like ozone and UV light break down DCF, but also found that these processes can create harmful byproducts.
- The study revealed that DCF can damage DNA and has other negative effects, showing that cleaning water containing DCF and similar pollutants can still be risky.
Objectives: Transcranial sonography has been used as a valid neuroimaging tool to diagnose Parkinson's disease (PD). This study aimed to develop a modified transcranial sonography (TCS) technique based on a deep convolutional neural network (DCNN) model to predict Parkinson's disease.
Methods: This retrospective diagnostic study was conducted using 1529 transcranial sonography images collected from 854 patients with PD and 775 normal controls admitted to the Second Affiliated Hospital of Soochow University (Suzhou, Jiangsu, China) between September 2019 and May 2022.
Article Synopsis
- The study aimed to investigate the link between substantia nigra (SN) hyperechogenicity and serum iron metabolism in patients with postural instability gait difficulty (PIGD) subtype of Parkinson's disease.
- It involved 95 PIGD patients divided into two groups based on SN hyperechogenicity and compared them with a control group of healthy individuals through blood tests for iron metabolism parameters.
- Results showed that serum ferritin, ceruloplasmin, and transferrin levels were lower in the PIGD groups than controls, with reduced ceruloplasmin levels linked to SN hyperechogenicity, suggesting a potential mechanism behind this condition.
Objective: This study aimed to explore the relationship between patients with obstructive sleep apnea (OSA) from subgroups of varying severity and substantia nigra (SN) hyperechogenicity as well as cerebral blood flow detected by transcranial sonography (TCS). The study also explored if there were differences in damage of the SN and in the cerebral blood flow between the bilateral sides.
Methods: Right-handed men diagnosed with OSA by polysomnography were recruited from August 2018 to August 2020.
Our study focused on three aspects to determine whether bilateral substantia nigra hyperechogenicity (SN+) is asymmetrical, whether the asymmetry of SN+ is related to the clinical features and whether there is variation in SN+ asymmetry during the progression of Parkinson disease (PD). This follow-up study included 234 patients with PD, who were divided into tremor PD (TD, n = 67) and non-tremor PD (NTD, n = 167) groups based on the Unified Parkinson's Disease Rating Scale (UPDRS) Part III. All participants underwent transcranial sonography (TCS) and clinical assessment.
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- - This study investigated how homocysteine (Hcy) levels relate to changes in brain structures, specifically the third ventricle (V3) and mesencephalic area (MA), in Parkinson's disease (PD) patients with cognitive impairment.
- - It included 101 PD patients and 20 controls, finding significant correlations between higher Hcy levels and wider V3 and more atrophy in MA, especially in those with cognitive issues.
- - The analysis indicated that higher Hcy levels were linked to a greater risk of both V3 dilatation and MA atrophy in PD patients, suggesting that elevated Hcy may contribute to brain degeneration in those with cognitive impairment.
Background: Rigidity is one of the major manifestations of Parkinson's disease (PD), but no quantitative and objective imaging method has been developed to measure rigidity. Ultrasound shear wave elastography (SWE) can reflect the stiffness of tissue by providing a quantitative index. Thus, we conducted this study to evaluate the potential clinical value of SWE in assessing rigidity in PD.
View Article and Find Full Text PDFBackground: Numerous studies have demonstrated that patients with Parkinson's disease (PD) have a higher prevalence of substantia nigra (SN) hyperechogenicity compared with controls. Our aim was to explore the neuroimaging characteristics of transcranial sonography (TCS) of patients with PD and those with PD with dementia (PDD). The correlation between the echogenicity of the SN and clinical symptoms in Chinese patients with PDD was also assessed.
View Article and Find Full Text PDFRecently, Parkinson's disease (PD) has been classified into three subtypes: postural instability gait difficulty (PIGD), tremor dominate (TD), and indeterminate PD. Transcranial sonography (TCS) is considered to be an important tool to diagnose PD. However, it is uncertain that whether there are differences in TCS image characteristics in different PD subtypes, so 373 idiopathic PD (188 PIGD, 108 TD, 77 indeterminate PD) were registered and received TCS in our investigation; also, the association between clinical characteristics and TCS results in different PD subtypes was analyzed.
View Article and Find Full Text PDFThe focus of the present study was to evaluate transrectal real-time tissue elastography (RTE)-targeted two-core biopsy coupled with peak strain index for the detection of prostate cancer (PCa) and to compare this method with 10-core systematic biopsy. A total of 141 patients were enrolled for evaluation. The diagnostic value of peak strain index was assessed using a receiver operating characteristic curve.
View Article and Find Full Text PDFBackground: Few studies have addressed whether abnormalities in the lenticular nucleus (LN) are characteristic transcranial sonography (TCS) echo features in patients with primary dystonia. This study aimed to explore alterations in the basal ganglia in different forms of primary focal dystonia.
Methods: cross-sectional observational study was performed between December 2013 and December 2014 in 80 patients with different forms of primary focal dystonia and 55 neurologically normal control subjects.