Publications by authors named "Cagdas Guducu"

The role of the cerebrovascular system in migraine pathogenesis is critical. Several studies have demonstrated alterations in the regional cerebral blood flow that persist during headache-free intervals. In the present study, we aimed to measure the prefrontal hemodynamic responses to the cognitive task in interictal episodic migraineurs.

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Article Synopsis
  • Objective assessment is crucial for diagnosing and treating taste disorders, with gERP being a promising tool compared to traditional psychophysical tests.
  • A study involved 44 patients with dysgeusia and 59 healthy participants, measuring their responses to salty solutions using a precise gustometer.
  • While gERPs did not show significant group differences in amplitudes or latencies, Time-Frequency Analyses revealed that controls had stronger low-frequency power and desynchronization in the alpha band, indicating altered taste sensations in dysgeusia patients.
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Olfaction is critical for maintaining daily life activities. It is crucial to measure olfactory performance for the diagnosis and treatment of certain neurodegenerative diseases. Moreover, impairments and a lack of quality in the olfactory system may indicate the early diagnosis of some diseases such as Parkinson's.

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Highly developed cognitive abilities are an important prerequisite for reaching elite athletic levels. This study aimed to investigate the effect of an acute sprint interval training (SIT) session on the cognitive performance of amateur and elite players. Eighteen amateur and ten elite male basketball players were included in this study.

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Context: Athletic skills such as balance are considered physical skills. However, these skills may not just improve by physical training, but also by mental training. The purpose of this study was to investigate the effects of mental training programs on balance skills and hemodynamic responses of the prefrontal cortex.

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This study compared the hemodynamic changes in the prefrontal cortex during sprint interval training (SIT) and recovery periods in sedentary and athletes. SIT was performed on a cycling ergometer on 12 male athletes and 9 sedentary participants. A functional near-infrared spectroscopy (fNIRS) device was used to record the hemodynamic changes of the prefrontal cortex throughout the protocol.

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In many species, social communication and mate choice are influenced by olfactory cues associated with the major histocompatibility complex (MHC). It has been reported that humans also respond to olfactory signals related to the human MHC-equivalent, the Human Leucocyte Antigen (HLA)-System, and exhibit an olfactory-mediated preference for potential mating partners with a dissimilar, disassortative, HLA-type compared to their own. The aim of this study was to investigate whether HLA-associated peptides, presented as volatile cues, elicit neuronal responses at the receptors in the human olfactory epithelium and can be consciously perceived.

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Newborns have a functioning sense of smell at birth, which appears to be highly significant for feeding and bonding. Still, little is known about the cerebral odor processing in this age group. Studies of olfactory function relied mostly on behavioral, autonomic, and facial responses of infants.

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The present study aimed to investigate whether the perception of still scenes in a virtual environment in congruent versus incongruent condition can be influenced by odors. Ninety healthy participants were divided into three groups, including two experimental virtual reality (VR) environments: a rose garden, an orange basket, and a control condition. In each VR condition, participants were exposed to a rose odor, an orange odor, or no odor, resulting in congruent, incongruent, and control conditions.

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Sleep is a very critical process that constitutes up to one third of daytime of a healthy adult. It is known to be an active period where body and brain is refreshed for the next day. It is both part of a larger cycle, i.

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The functions of the sensory systems on disabled people have been one of the most investigated topics in brain research. In these studies, mostly visual stimuli had been employed while investigating the deaf participants. Limited number of electrophysiological studies revealed better visual sensory processing in deaf participants.

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Parkinson's Disease (PD) is a common neurodegenerative disorder affecting the function of dopaminergic cells in basal ganglia. Besides the motor symptoms, tremor, and dysfunction of sensory systems. In the literature, there was limited studies which investigates the basic sensorial processing in PD.

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In this study, 64-channel single trial auditory brain oscillations (STABO) have been firstly analyzed by using complexity metrics to observe the effect of musical experience on brain functions. Experimental data was recorded from eyes-opened volunteers during listening the musical chords by piano. Complexity estimation methods were compared to each other for classification of groups (professional musicians and non-musicians) by using both classifiers (support vector machine (SVM), Naive Bayes (NB)) and statistical tests (one-way ANOVA) with respect to electrode locations.

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In a classical dichotic listening paradigm, besides auditory brain asymmetry, cognitive functions such as attention and conflict resolution play a major role. The aim of this study is to reveal the possible haemodynamic mechanisms of higher attentional performance in prefrontal cortex during dichotic listening test. Twenty-six healthy participants underwent a dichotic listening task in three sessions; non-forced attention, attention focused to right ear, and attention focused to left ear.

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The aim of the present study was to investigate whether repetitive aversive odor conditioning induced changes at the level of the peripheral olfactory system in humans. A total of 51 volunteers participated. A pair of indistinguishable odor enantiomers [(+)-rose oxide and (-)-rose oxide] were used as stimuli.

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The ability of humans to discriminate enantiomeric odour pairs is substance -specific. Current literature suggests that psychophysical discrimination of odour enantiomers mainly depends on the peripheral processing at the level of the olfactory sensory neurons (OSN). To study the influence of central processing in discrimination, we investigated differences in the electrophysiological responses to psychophysically indistinguishable (+)- and (-)- rose oxide enantiomers at peripheral and central-nervous levels in humans.

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Single bout of exercise can improve the performance on cognitive tasks. However, cognitive responses may be controversial due to different type, intensity, and duration of exercise. In addition, the mechanism of the effect of acute exercise on brain is still unclear.

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The relationship between Parkinson's disease (PD) and olfactory dysfunction has been investigated via psychophysical and electrophysiological assessments. Despite the increasing number of electrophysiological studies focusing on olfactory function, there are still some limitations to observe the chemosensory event-related potentials (CSERP), which are electrophysiological responses of the brain to olfactory and trigeminal stimulations, because of the low sensitivity (low signal-to-noise ratio). Recent studies attempted to establish new techniques to increase the sensitivity for evaluating the CSERP and brain responsiveness.

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Objective: Kallmann syndrome (KS) is a genetic disorder with the distinctive features of hyposmia or anosmia and hypogonadotropic hypogonadism. Though hyposmia/anosmia can be evaluated by both objective and subjective smell tests, there is no study comparing these two methods in KS. The aim of the present case series was to discuss the results of objective and subjective smell tests and compare them to volumetric magnetic resonance imaging (MRI).

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