Publications by authors named "Cador B"

Background: Older patients often experience adverse drug events (ADEs) after discharge that may lead to unplanned readmission. Medication Reconciliation (MR) reduces medication errors that lead to ADEs, but results on healthcare utilization are still controversial. This study aimed to assess the effect of MR at discharge (MRd) provided to patients aged over 65 on their unplanned rehospitalization within 30 days and on both patients' experience of discharge and their knowledge of their medication.

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Introduction: Patients admitted from emergency units represent a large portion of the population in internal medicine departments. The aim of this study is to identify characteristics of patients and organization of these departments.

Methods: Between June 29th and July 26th 2015, voluntary internal medicine departments from the SiFMI group prospectively filled anonymized internet forms to collect data of each patients admitted in their ward from emergency units, during seven consecutive days.

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Patients with type 1 Gaucher disease (GD1) present thrombocytopenia, anemia, organomegaly, and bone complications. Most experts consider that the less aggressive forms do not require specific treatment. However, little is known about the disease course of these forms.

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Article Synopsis
  • Gaucher disease (GD) is a rare genetic disorder linked to a deficiency in the enzyme glucocerebrosidase, which can lead to immunoglobulin abnormalities like polyclonal and monoclonal gammopathy in patients.
  • A study examined 278 GD patients over an average of 19 years, finding that nearly half exhibited polyclonal gammopathy and about a third showed monoclonal gammopathy, with age at diagnosis being a significant risk factor for developing monoclonal gammopathy.
  • The research concluded that while immunoglobulin abnormalities occur commonly in GD, they are not linked to the severity of the disease, but ongoing monitoring is essential due to the potential risk of hematologic cancers developing in these patients.
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Schnitzler syndrome is an auto-inflammatory disease defined by chronic urticarial eruption and monoclonal gammopathy. F fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) is often performed, but its utility in Schnitzler syndrome has not been specifically investigated. The aim of this study was to determine whether PET/CT is informative in the diagnosis and follow-up of Schnitzler syndrome relative to other imaging techniques, including bone scans.

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Introduction: Adult-onset Still's Disease is a rare multisystemic inflammatory disease characterized by fever, maculo-papular erythematous rash and arthralgia. Adult-onset Still's disease is a diagnosis of exclusion.

Case Report: We report the case of a 33 years old man, hospitalized for fever, arthralgia and throat manifestations, leading to Adult-onset Stills's Disease diagnosis.

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The aim of this study is to assess the long-term effectiveness and safety of IL1Ra in Schnitzler syndrome (SchS). Between 2010 and 2012, we performed a nationwide survey among French internal medicine departments to identify SchS patients. We retrospectively analyzed the long-term efficacy and safety of IL1Ra and the outcome of patients that did not receive this treatment.

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Introduction: General practitioners report difficulties to work efficiently with hospital physicians. We created a phone number dedicated to general practitioners to contact directly a hospital physician in the general internal medicine department entitled "quick diagnostic and therapeutic assistance". The aim of this study was to assess the first year activity of this professional support and its impact on general practitioners.

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Purpose: A deterioration of the general condition, a prolonged fever or an unexplained inflammatory syndrome are frequent reasons for hospitalization in a internal medicine unit. In these situations, it is not rare to make a diagnosis of cancer.

Patients And Methods: A descriptive study was carried out over a three years period (1st October 1999 to 30th September 2002) in an internal medicine unit.

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Introduction: Monoclonal gammopathies of undetermined significance (MGUS) occur in up to 1% of persons aged 50 years or older. The risk of its progression to multiple myeloma or related disorders is also approximately 1% per year.

Objectives: Our study had two aims: to describe the risk of malignant progression of patients examined in our center for MGUS, and to identify predictors of this malignant progression.

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Iron deficiency is the most widespread nutritional disorder in the world, affecting an estimated 1.2 billion people. Its prevalence is particularly high in developing countries (Africa, Asia, South America), but iron deficiency remains a public health problem in industrialised countries.

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Introduction: Infectious aortitis remains a rare disease. It is characterized by an endarteritis of infectious origin generally followed by the development of a so called mycotic aneurysm. Those infectious aneurysms account for 0.

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Objectives: To study the frequency of a factor of immunodepression in patients with tuberculosis, the differences in presentation, and the diagnosis and therapeutic management according to the immune status.

Methods: Retrospective study of the files of patients hospitalised in the University Hospital Centre of Rennes in 1998 for a Mycobacterium tuberculosis infection. Comparison of two populations, immunodepressed versus non immunodepressed.

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Background: Raynaud's phenomenon (RP) is a frequent vascular paroxysmal syndrome of the extremities. Generally benign, the condition is called Raynaud's disease (RD), which may reveal a connective tIssue disease, particularly systemic sclerosis (SS). We evaluated digital blood flow in patients with RD and SS using color Doppler ultrasound.

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Introduction: The frequency of amyloidosis is not well known in France. We compiled a register of amyloidosis diagnosed from 1995 to 1999 in the University Hospital of Rennes.

Patients And Methods: This retrospective study was performed between 01 January 1995 and 31 december 1999.

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Introduction: The responsibility of cannabis in juvenile thromboangeitis has been suggested for few years. We describe four new cases.

Exegesis: Young men presented with distal arteriopathy of the lower limbs in 3 cases, and of the left upper limb in the remaining patient.

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Objectives And Methods: A retrospective study of 45 patients with Clostridium difficile infection over a 4-year period in a department of Internal Medicine.

Results: Mean age was 79 years; sex-ratio (F/M)=1.5; 38% of the patients had neurological or severe psychiatric disorders; 20% had a neoplastic disease.

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Introduction: Hemorrhages beneath the dura define a subdural hematoma.

Exegesis: The course of chronic subdural hematoma may be asymptomatic for many months before diagnosis. Recovery is observed in 80% of patients after surgery.

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