Publications by authors named "Cade Beck"
Article Synopsis
- The study investigates how varying concentrations of fibroblast growth factor (FGF) affect the migration of glia cells critical for vision in Drosophila melanogaster, using a microfluidic device for precision analysis.
- Findings reveal that glia cells are directed toward higher FGF concentrations, and their migration is dependent on coordinated movement with neuronal progenitors to travel long distances effectively.
- The research highlights the advantage of microfluidic systems over traditional methods, providing insights into the migratory behavior of glia, which could open up potential therapeutic strategies for neural development issues.
Glial tumors have demonstrated abilities to sustain growth recruitment of glial progenitor cells (GPCs), which is believed to be driven by chemotactic cues. Previous studies have illustrated that mouse GPCs of different genetic backgrounds are able to replicate the dispersion pattern seen in the human disease. How GPCs with genetic backgrounds transformed by tumor paracrine signaling respond to extracellular cues migration is largely unexplored, and remains a limiting factor in utilizing GPCs as therapeutic targets.
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