Publications by authors named "Cabral D"

Introduction: Complete radical resection is crucial for successfully treating thymic carcinomas. However, when the invasion of the great vessels or the heart in Masaoka III and IV stages occurs, the management poses more challenges. The R0 resection often requires neoadjuvant treatment.

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Cognitive and physical stress have significant effects on brain health, particularly through their influence on the central executive network (CEN). The CEN, which includes regions such as the dorsolateral prefrontal cortex, anterior cingulate cortex and inferior parietal lobe, is central to managing the demands of cognitively challenging motor tasks. Acute stress can temporarily reduce connectivity within the CEN, leading to impaired cognitive function and emotional states.

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The application of external electric fields to influence chemical reactions at electrode interfaces has attracted considerable interest in recent years. However, the design of electric fields to achieve highly efficient and selective catalytic systems, akin to the optimized fields found at enzyme active sites, remains a significant challenge. Consequently, there has been substantial effort in probing and understanding the interfacial electric fields at electrode/electrolyte interfaces and their effect on adsorbates.

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Background: Carotid intima-media thickness (IMT) is a measure of atherosclerosis and a predictor of vascular diseases. Traditional vascular risk factors and genetic variants do not completely explain the variation in carotid IMT. We sought to identify epigenetic factors that may contribute to the remaining carotid IMT variability.

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Arthropod-borne viral diseases are acute febrile illnesses, sometimes with chronic effects, that can be debilitating and even fatal worldwide, affecting particularly vulnerable populations. Indigenous communities face not only the burden of these acute febrile illnesses, but also the cardiovascular complications that are worsened by urbanization. A cross-sectional study was conducted in an Indigenous population in the Northeast Region of Brazil to explore the association between arboviral infections (dengue, chikungunya, and Zika) and cardiac biomarkers, including cardiotrophin 1, growth differentiation factor 15, lactate dehydrogenase B, fatty-acid-binding protein 3, myoglobin, N-terminal pro-B-type natriuretic peptide, cardiac troponin I, big endothelin 1, and creatine kinase-MB, along with clinical and anthropometric factors.

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Unlabelled: Substance use disorder (SUD) is a chronically relapsing disorder; thus, individuals with SUD may require several attempts before achieving abstinence. The goal of the present study was to investigate what variables are associated with the number of quit attempts before successful abstinence was achieved. Data were collected from 421 International Quit & Recovery Registry participants.

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Background: This meta-review aimed to synthesize the evidence of the effects of exercise on anxiety and depression symptoms amongst adults with cancer, and cancer-survivors, comparing effects sizes between meta-analysis.

Methods: Major databases were searched up to February 9, 2024 for meta-analyses evaluating the effects of exercise, using anxiety and/or depression scales. Effect size (ES) values were calculated as standardized differences in the means and expressed as the Standardized Mean Difference (SMD) with the 95% confidence interval (95%CI).

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Article Synopsis
  • The study explores how physical activity influences quality of life (QOL) and delay discounting in individuals recovering from substance use disorders.
  • Results indicate that higher physical activity levels are related to lower delay discounting rates and improved physical and environmental QOL.
  • Delay discounting is suggested to mediate the connection between physical activity and specific QOL domains, highlighting the importance of exercise in recovery.
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Objective: We aimed to study the disease course, outcomes, and predictors of outcome in pediatric-onset antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) affecting the kidneys.

Methods: Patients eligible for this study had a diagnosis of granulomatosis with polyangiitis (GPA), microscopic polyangiitis, or ANCA-positive pauci-immune glomerulonephritis, were 18 years or younger at diagnosis, had renal disease defined by biopsy or dialysis dependence, and had clinical data at diagnosis and at either 12 or 24 months. Ambispective data from A Registry for Children with Vasculitis/Pediatric Vasculitis Initiative Registry was used.

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  • The study explores simulating chemical reaction dynamics using a superconducting Kerr-cat device, focusing on proton-transfer reactions across a free energy barrier.
  • Traditional rate theories miss crucial aspects like quantum tunneling and recrossing, which this study aims to address.
  • Results show the approach effectively replicates dynamics in benchmark systems like malonaldehyde dimers and DNA base pairs, showcasing its potential for advanced chemical reaction simulations.
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  • Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to long-lasting inflammation in the nasal area and often requires endoscopic sinus surgery (ESS) when treatments fail, with recurrence rates between 5% and 60%.
  • A study examined 130 patients who had ESS, finding a 5-year recurrence rate of 35.4% and 17.7% needing revision surgery, while identifying several factors linked to poor outcomes.
  • Key predictors for recurrence included having asthma, frontal sinus involvement, high Lund-Mackay and Endoscopic Nasal Polyps Scores, and elevated eosinophilia in blood tests, indicating more complicated cases of CRSwNP.
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Background: Substance use disorder (SUD) and pain are highly comorbid conditions and several pain indices (e.g., pain intensity) are associated with an increased risk of relapse.

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  • The study compares the effectiveness and toxicity of two treatments, rituximab (RTX) and cyclophosphamide (CYC), for pediatric patients with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA).
  • It analyzes data from 104 patients and finds no significant difference in remission rates or severe adverse events between the two treatment groups.
  • Limitations of the study include the lack of standardized treatment protocols and the retrospective nature of the analysis.
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  • The study aimed to find if lower contrast enhancement on postoperative MRI is linked to a higher chance of complications in patients undergoing nasoseptal flap (NSF) reconstruction after surgery.
  • It involved a review of patients who had an endoscopic endonasal approach with NSF reconstruction, assessing their MRIs for enhancement scores that indicate how well the flap is healing.
  • Results showed that patients with lower enhancement scores had significantly higher odds of complications, suggesting that MRI enhancement levels could help surgeons predict patient outcomes more effectively.
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Choroidal Infiltrates (Cis) detection is traditionally done using invasive imaging. We herein report the usage of topographic choroidal thickness maps (ChT maps) and en face swept-source Optical Coherence Tomography (OCT) as a rapid and non-invasive technique to monitor Cis in a patient with Chronic Lymphocytic Leukemia.

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Lung cancer is the most common cause of cancer death in Portugal. The Dutch-Belgian lung cancer screening (LCS) study (NELSON), the biggest European LCS study, showed a lung cancer mortality reduction in a high-risk population when being screened. In this study, the cost-effectiveness of LCS, based on the NELSON study protocol and outcomes, was evaluated compared with no screening in Portugal.

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This randomized controlled trial investigated the effectiveness of an affect-adjusted, supervised, multimodal, online, and home-based exercise group protocol as an adjunct therapy to antidepressants on depressive symptoms, cardiorespiratory fitness, and side effects related to antidepressants in adults with major depression (MDD, diagnosed by a clinician). Depressive symptom scales were administered by a psychiatrist and self-reported. A health-related measure (i.

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Article Synopsis
  • Inherited retinal dystrophies (IRDs) are the leading cause of blindness in families in the Western world, making molecular diagnosis crucial due to their genetic diversity.
  • A nationwide survey in Portugal revealed an IRD prevalence of about 0.031%, with most healthcare providers managing primarily adult patients, and non-syndromic retinitis pigmentosa being the most common diagnosis.
  • Only a small number of providers use the national IRD registry, but there’s overall interest in participating, highlighting the need for better data collection and the potential for improved patient care and therapy access.
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Objectives: We examined adverse event (AE) reports relating to cabotegravir/rilpivirine (CAB/RPV) in the US FDA Adverse Event Reporting System (FAERS), focusing on therapeutic failure (TF) and non-therapeutic failure (NTF) outcomes.

Methods: FAERS is a database of AE and medication error reports from post-marketing surveillance. The study was granted exempt approval by the Binghamton University Institutional Review Board.

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An increasing number of consumers demand healthier, more convenient, and sustainable food products, including rice, a staple worldwide. Food manufacturers have responded to this trend by considering food's intrinsic and extrinsic aspects. This study evaluated the importance of variety, processing, and claims on willingness to try ready-to-eat rice (RTE-rice).

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Article Synopsis
  • * These devices can simulate chemical structures and dynamics by mapping system Hamiltonians with bosonic operators.
  • * The review discusses recent advancements and future possibilities for using these devices in solving complex chemical issues, like molecular spectra and electronic structure calculations.
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Background: Research on delay discounting (DD) is mixed on whether DD is a domain-specific component related to specific behaviors or a domain-general process that cuts across various behaviors. A pivotal group to test the associations between DD and unhealthy behaviors is individuals in recovery from substance use disorders (SUD), as they are moving away from a disorder toward a healthier state.

Methods: Individuals in SUD recovery (n = 317) completed the Temptation Scale, the Health Behaviors Questionnaire, and an Adjusting Delay Discounting Task.

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