Stabilization of Chromium Waste by Solidification into Cement Composites.

This article deals with the study of hazardous chromium leaching, stabilized/solidified by cement CEM II after 28 days of curing, in an acidic environment. The mortars subjected to this study were investigated by X-ray diffraction (XRD) characterization to evaluate the influence of chromium waste on their mineralogical structure. In the study range (0.

Nano-Clay Platelet Integration for Enhanced Bending Performance of Concrete Beams Resting on Elastic Foundation: An Analytical Investigation.

Acknowledging the growing impact of nanotechnologies across various fields, this engaging research paper focuses on harnessing the potential of nano-sized materials as enhancers for concretes. The paper emphasizes the strategic integration of these entities to comprehensively improve the strength and performance of concrete matrixes. To achieve this, an analytical study is conducted to investigate the static behavior of concrete beams infused with different types of clay nano-platelets (NC's), employing quasi-3D beam theory.

External Confined Concrete Cylinders Behavior under Axial Compression Using CFRP Wrapping.

Carbon-fiber-reinforced polymer (CFRP) is a composite material used to mend and strengthen concrete structural elements in civil engineering. The prime aim of this experimental study is to investigate the comportment of confined concrete cylinders (CCC) under uniaxial loads by altering the concrete strength, the CFRP angle orientation, and the volumetric ratio, following the externally bonded reinforcement technique (EBR). We present the results of the confinement effect and failure mechanisms issue of more than 150 specimens of CFRP confined concrete cylinders that have been undertaken and in which several parameters were altered.

Design of a machine learning model for the precise manufacturing of green cementitious composites modified with waste granite powder.

In this study, a machine learning model for the precise manufacturing of green cementitious composites modified with granite powder sourced from quarry waste was designed. For this purpose, decision tree, random forest and AdaBoost ensemble models were used and compared. A database was created containing 216 sets of data based on an experimental study.

Decreasing the hazardous effect of waste quartz powder and the toxicity of epoxy resin by its synergistic application in industrial coatings.

Quartz powder sourced from industrial wastes is very hazardous. It is because it contains large amounts of fine particles. Thus, it has the potential to cause cancer and nervous system impact on humans and animals.

The Effect of Basalt Aggregates and Mineral Admixtures on the Mechanical Properties of Concrete Exposed to Sulphate Attacks.

In this study, basalt, which is common around Diyarbakır province (Turkey), is used as concrete aggregate, waste materials as mineral additives and Portland cement as binding material to prepare concrete mixes. This paper aims to determine the proper admixture levels and usability of Diyarbakır basalt in concrete mixtures based on mechanical, physical and chemical tests. Thus, in order to determine the strength and durability performance of concrete mixtures with Diyarbakır basalt as aggregate, 72 sample cubes of 150 mm were prepared in three groups: mineral-free admixture (MFA), 10% of cement amount substituted for silica fume (SFS) and 20% for fly ash (FAS) as waste material.

The Isotropic Material Design of In-Plane Loaded Elasto-Plastic Plates.

This paper puts forward a new version of the Isotropic Material Design method for the optimum design of structures made of an elasto-plastic material within the Hencky-Nadai-Ilyushin theory. This method provides the optimal layouts of the moduli of isotropy to make the overall compliance minimal. Thus, the bulk and shear moduli are the only design variables, both assumed as non-negative fields.

A Comparative Study for the Prediction of the Compressive Strength of Self-Compacting Concrete Modified with Fly Ash.

Artificial intelligence and machine learning are employed in creating functions for the prediction of self-compacting concrete (SCC) strength based on input variables proportion as cement replacement. SCC incorporating waste material has been used in learning approaches. Artificial neural network (ANN) support vector machine (SVM) and gene expression programming (GEP) consisting of 300 datasets have been utilized in the model to foresee the mechanical property of SCC.

Randomized Phase II Trial of MIBG Versus MIBG, Vincristine, and Irinotecan Versus MIBG and Vorinostat for Patients With Relapsed or Refractory Neuroblastoma: A Report From NANT Consortium.

Purpose: I-metaiodobenzylguanidine (MIBG) is an active radiotherapeutic for neuroblastoma. The primary aim of this trial was to identify which of three MIBG regimens was likely associated with the highest true response rate.

Patients And Methods: Patients 1-30 years were eligible if they had relapsed or refractory neuroblastoma, at least one MIBG-avid site, and adequate autologous stem cells.

Application of Novel Machine Learning Techniques for Predicting the Surface Chloride Concentration in Concrete Containing Waste Material.

Structures located on the coast are subjected to the long-term influence of chloride ions, which cause the corrosion of steel reinforcements in concrete elements. This corrosion severely affects the performance of the elements and may shorten the lifespan of an entire structure. Even though experimental activities in laboratories might be a solution, they may also be problematic due to time and costs.

Mechanical and Microstructural Properties of Ordinary Concrete with High Additions of Crushed Glass.

This study investigates the use of crushed glass waste as partial cement replacement in ordinary concretes. Six concrete mixes were designed and prepared: a reference without substitution and five substitution percentages of crushed glass waste ranging from 5% to 25%. The made concrete mix design underwent different tests, namely: slump test, mechanical strength, thermogravimetric analysis (TGA), X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET) determination and finally, water porosimetry, in order to evaluate the influence of the use of crushed glass waste on the properties of fresh and hardened concrete.

Evidence for a Diagenetic Origin of Vera Rubin Ridge, Gale Crater, Mars: Summary and Synthesis of 's Exploration Campaign.

This paper provides an overview of the rover's exploration at Vera Rubin ridge (VRR) and summarizes the science results. VRR is a distinct geomorphic feature on lower Aeolis Mons (informally known as Mount Sharp) that was identified in orbital data based on its distinct texture, topographic expression, and association with a hematite spectral signature. conducted extensive remote sensing observations, acquired data on dozens of contact science targets, and drilled three outcrop samples from the ridge, as well as one outcrop sample immediately below the ridge.

The Nature-Inspired Metaheuristic Method for Predicting the Creep Strain of Green Concrete Containing Ground Granulated Blast Furnace Slag.

The aim of this study was to develop a nature-inspired metaheuristic method to predict the creep strain of green concrete containing ground granulated blast furnace slag (GGBFS) using an artificial neural network (ANN)model. The firefly algorithm (FA) was used to optimize the weights in the ANN. For this purpose, the cement content, GGBFS content, water-to-binder ratio, fine aggregate content, coarse aggregate content, slump, the compaction factor of concrete and the age after loading were used as the input parameters, and in turn, the creep strain () of the GGBFS concrete was considered as the output parameters.

Phase II Trial of Alisertib in Combination with Irinotecan and Temozolomide for Patients with Relapsed or Refractory Neuroblastoma.

Purpose: In phase I testing, alisertib tablets with irinotecan and temozolomide showed significant antitumor activity in patients with neuroblastoma. This study sought to confirm activity of this regimen; evaluate an alisertib oral solution; and evaluate biomarkers of clinical outcomes.

Patients And Methods: We conducted a two-stage phase II trial of alisertib tablets (60 mg/m/dose × 7 days), irinotecan (50 mg/m/dose i.

Hybrid Silicon-Based Organic/Inorganic Block Copolymers with Sol-Gel Active Moieties: Synthetic Advances, Self-Assembly and Applications in Biomedicine and Materials Science.

Hybrid silicon-based organic/inorganic (multi)block copolymers are promising polymeric precursors to create robust nano-objects and nanomaterials due to their sol-gel active moieties via self-assembly in solution or in bulk. Such nano-objects and nanomaterials have great potential in biomedicine as nanocarriers or scaffolds for bone regeneration as well as in materials science as Pickering emulsifiers, photonic crystals or coatings/films with antibiofouling, antibacterial or water- and oil-repellent properties. Thus, this Review outlines recent synthetic efforts in the preparation of these hybrid inorganic/organic block copolymers, gives an overview of their self-assembled structures and finally presents recent examples of their use in the biomedical field and material science.

Similar but not the same: metal concentrations in hair of three ecologically similar, forest-dwelling bat species (Myotis bechsteinii, Myotis nattereri, and Plecotus auritus).

Recently, a number of studies demonstrated the suitability of hair analysis to assess metal exposure of bats. As many bat species are endangered, such a non-destructive method is particularly suited for this taxon. The present study analyzed the levels of two non-essential (cadmium and lead) and four essential metals (copper, manganese, molybdenum, and zinc) in hairs of three ecologically similar, sympatric bat species, Bechstein's bat (Myotis bechsteinii), Natterer's bat (Myotis nattereri), and Brown long-eared bat (Plecotus auritus) from an area in Central Hesse (Germany), as well as metal concentrations in soil samples from the bats' foraging habitats.

The Isotropic and Cubic Material Designs. Recovery of the Underlying Microstructures Appearing in the Least Compliant Continuum Bodies.

The paper discusses the problem of manufacturability of the minimum compliance designs of the structural elements made of two kinds of inhomogeneous materials: the isotropic and cubic. In both the cases the unit cost of the design is assumed as equal to the trace of the Hooke tensor. The Isotropic Material Design (IMD) delivers the optimal distribution of the bulk and shear moduli within the design domain.

Expression of Five Neuroblastoma Genes in Bone Marrow or Blood of Patients with Relapsed/Refractory Neuroblastoma Provides a New Biomarker for Disease and Prognosis.

We determined whether quantifying neuroblastoma-associated mRNAs (NB-mRNAs) in bone marrow and blood improves assessment of disease and prediction of disease progression in patients with relapsed/refractory neuroblastoma. mRNA for CHGA, DCX, DDC, PHOX2B, and TH was quantified in bone marrow and blood from 101 patients concurrently with clinical disease evaluations. Correlation between NB-mRNA (delta cycle threshold, Δ, for the geometric mean of genes from the TaqMan Low Density Array NB5 assay) and morphologically defined tumor cell percentage in bone marrow, I-meta-iodobenzylguanidine (MIBG) Curie score, and CT/MRI-defined tumor longest diameter was determined.

A Phase I New Approaches to Neuroblastoma Therapy Study of Buthionine Sulfoximine and Melphalan With Autologous Stem Cells for Recurrent/Refractory High-Risk Neuroblastoma.

Background: Myeloablative therapy for high-risk neuroblastoma commonly includes melphalan. Increased cellular glutathione (GSH) can mediate melphalan resistance. Buthionine sulfoximine (BSO), a GSH synthesis inhibitor, enhances melphalan activity against neuroblastoma cell lines, providing the rationale for a Phase 1 trial of BSO-melphalan.

Hybrid Polymer-Network Hydrogels with Tunable Mechanical Response.

Hybrid polymer-network gels built by both physical and covalent polymer crosslinking combine the advantages of both these crosslinking types: they exhibit high mechanical strength along with excellent fracture toughness and extensibility. If these materials are extensively deformed, their physical crosslinks can break such that strain energy is dissipated and irreversible fracturing is restricted to high strain only. This mechanism of energy dissipation is determined by the kinetics and thermodynamics of the physical crosslinking contribution.

Phase I Study of the Aurora A Kinase Inhibitor Alisertib in Combination With Irinotecan and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma: A NANT (New Approaches to Neuroblastoma Therapy) Trial.

Purpose: Alisertib is an oral Aurora A kinase inhibitor with preclinical activity in neuroblastoma. Irinotecan and temozolomide have activity in patients with advanced neuroblastoma. The goal of this phase I study was to determine the maximum tolerated dose (MTD) of alisertib with irinotecan and temozolomide in this population.

[Bleeding during central venous catheterization : Cannot intubate, cannot ventilate due to massive cervical hematoma].

Central venous catheterization is an invasive procedure which can be associated with severe complications. These include in particular unsuccessful arterial puncture and vascular injuries, which in addition to loss of blood can lead to massive soft tissue swelling. A 63-year-old female patient developed massive cervical bleeding during ultrasound-guided internal jugular vein puncture and the rapidly enlarging hematoma led to compromisation of the airway.

Reduction of metal exposure of Daubenton's bats (Myotis daubentonii) following remediation of pond sediment as evidenced by metal concentrations in hair.

Transfer of contaminants from freshwater sediments via aquatic insects to terrestrial predators is well documented in spiders and birds. Here, we analyzed the metal exposure of Myotis daubentonii using an urban pond as their preferred foraging area before and after a remediation measure (sediment dredging) at this pond. Six metal elements (Zn, Cu, Cr, Cd, Pb and Ni) were measured in the sediment of the pond, in EDTA extracts of the sediment and in hair samples of M.

Trace metal concentrations in hairs of three bat species from an urbanized area in Germany.

Metal-contaminated soils and sediments are widespread in urbanized areas due to atmospheric deposition close to emission sources. These metals are bio-available for organisms, e.g.

Phase I Study of Vorinostat as a Radiation Sensitizer with 131I-Metaiodobenzylguanidine (131I-MIBG) for Patients with Relapsed or Refractory Neuroblastoma.

Purpose: (131)I-metaiodobenzylguanidine (MIBG) is a radiopharmaceutical with activity in neuroblastoma. Vorinostat is a histone deacetylase inhibitor that has radiosensitizing properties. The goal of this phase I study was to determine the MTDs of vorinostat and MIBG in combination.