Publications by authors named "CY Hwang"

The objective of this study was to evaluate whether supplementation with probiotics over a 2-week period stabilizes the gut microbiota in dogs following prolonged cefovecin treatment. A significant number of clinical veterinarians prescribe oral probiotics to dogs in conjunction with systemic antibiotics with the intention of protecting against gut dysbiosis. The effects of antibiotics and probiotics in dogs have not been extensively studied, however, and the optimal treatment for gut dysbiosis remains uncertain.

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Haloarchaea represents a unique group of microorganisms that have adapted to thrive in high-salt environments. These microbes produce distinctive biomolecules, some of which exhibit extraordinary properties. One such biomolecule is bacterioruberin, a prominent red-pigmented C carotenoid commonly found in halophilic archaea, renowned for its antioxidant properties and potential as a functional resource.

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This study simultaneously measured the taxonomic diversity of bacterial communities in both seawater and PM aerosol samples collected from the Northern Pacific Ocean during a cruise covering 7724 km between 37°N 126°E and 58°N 179°E. The relative abundance of Proteobacteria, Cyanobacteria, and Firmicutes were found to be more prevalent in aerosol samples (39 ± 16 %, 5.1 ± 1.

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  • A new archaeon named MBLA0158 was discovered in a solar saltern in Korea, characterized by its red pigmentation and ability to thrive in highly saline environments.
  • * The strain grows best at temperatures of 37°C and in 20% salt concentration, and molecular analysis shows it is closely related to Halobellus inordinatus with 96% genetic similarity.
  • * It is proposed as a new species, Halobellus rubicundus sp. nov., based on unique genetic features and a distinct genomic profile.
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  • - An 8-year-old spayed female Maltese dog was referred for treatment due to persistent, itchy, ulcerative skin lesions and chronic ear infections lasting four months.
  • - A biopsy showed skin damage and a bacterial infection that was resistant to multiple drugs; treatment with ciprofloxacin led to improvement of the skin lesions.
  • - The case suggests that infections may trigger erythema multiforme in dogs, which is a rare condition that's not well described in veterinary literature.
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  • Melasma is a challenging skin condition characterized by hyperpigmentation, and this study aimed to observe changes in melanin and melanocytes after laser treatment using optical coherence tomography (OCT).
  • Eight female patients with melasma in Taiwan were analyzed, categorized by type of melasma, and received tailored treatment with sequential OCT imaging taken over 8 weeks.
  • Results indicated significant improvement in the Melasma Area Severity Index (MASI) score, but OCT showed no major changes in melanin; however, there was a decrease in both the length and width of dendritic melanocytes in lesional skin.
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Carotenoids are natural pigments utilized as colourants and antioxidants across food, pharmaceutical and cosmetic industries. They exist in carbon chain lengths of C, C, C and C, with C variants being the most common. Bacterioruberin (BR) and its derivatives are part of the less common C carotenoid group, synthesized primarily by halophilic archaea.

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In this study, a novel species within the genus was isolated from the coastal soil of Dokdo (Seodo) Island and investigated. We elucidated the novel species, designated MBLB3053, through genomic analysis of novel functional microbial resources. Cells were gram-negative, non-motile, and coccoid, and the colony was light orange in color.

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Importance: Feline calicivirus (FCV)-associated viral systemic disease (VSD) is a severe systemic disease caused by virulent FCV strains and has a very poor prognosis.

Objective: To evaluate the clinical characteristics of a nosocomial FCV-VSD outbreak involving 18 cats in Korea.

Methods: Medical records of cats diagnosed with FCV-VSD from March to September 2018 at a referral veterinary hospital were reviewed.

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Dark matter is believed to be the essential building blocks of galaxy formation. While instances of galaxies lacking dark matter have been observed, these occurrences are typically linked to specific formation mechanisms, making them stand out as unique cases. In spiral galaxies, the presence of flat rotation curves is a common observation, indicating the need for dark matter to support these dynamics.

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A Gram-stain-negative, aerobic, rod-shaped and motile strain HL-JVS1, was isolated from the gastric tract of a juvenile Pacific white shrimp. Molecular phylogenetic analysis based on 16S rRNA gene sequences of strain HL-JVS1 revealed its affiliation with the genus Pleionea, with close relatives including Pleionea mediterranea MOLA115 (97.5%) and Pleionea sediminis S1-5-21 (96.

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The direct effects and antimicrobial activity of synthetic antimicrobial peptides (AMPs) obtained from dogs, including cBD, cBD103, and cCath, against wild-type strain PAO1 and canine keratinocytes were analyzed. Antibacterial effects on planktonic bacteria were assessed by determining the minimum bactericidal concentrations (MBCs) of AMPs and by a time-kill assay. Antibiofilm effects were assessed using the microtiter plate assay.

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Background: A central challenge in biology is to discover a principle that determines individual phenotypic differences within a species. The growth rate is particularly important for a unicellular organism, and the growth rate under a certain condition is negatively associated with that of another condition, termed fitness trade-off. Therefore, there should exist a common molecular mechanism that regulates multiple growth rates under various conditions, but most studies so far have focused on discovering those genes associated with growth rates under a specific condition.

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Haloarchaea produce bacterioruberin, a major C carotenoid with antioxidant properties that allow for its potential application in the food, cosmetic, and pharmaceutical industries. This study aimed to optimize culture conditions for total carotenoid, predominantly comprising bacterioruberin, production using Halorubrum ruber MBLA0099. A one-factor-at-a-time and statistically-based experimental design were applied to optimize the culture conditions.

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Background: Hair cycle arrest (HCA) is a chronic alopecic disorder in dogs. Clinical responses vary and are often insufficient. Microneedling (MN) has been used as a successful treatment for HCA in dogs; ideal protocols have not yet been established.

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The novel bacterial strain MBLB1776 was isolated from marine mud in Uljin, the Republic of Korea. Cells were Gram-positive, spore-forming, non-motile, and non-flagellated rods. Growth was observed at a temperature range of 10-45 °C, pH range of 6.

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  • Carbapenemase-producing Klebsiella pneumoniae (CPKP) is a highly resistant bacteria that poses a serious health risk, especially since it can be transmitted from companion dogs to humans.
  • Researchers performed a whole-genome analysis on two CPKP isolates, revealing multiple plasmids and a collection of antimicrobial resistance (AMR) genes, indicating a complex genetic structure.
  • The study highlights the emergence of a new CPKP strain (ST378) with a higher prevalence of AMR genes, emphasizing the urgent need for enhanced surveillance and control strategies to combat this public health threat.
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A novel Gram-stain-negative, aerobic, rod-shaped bacterium, designated as HL-NP1, was isolated from the surface water of the northwestern Pacific Ocean after enrichment cultivation using the organic phosphorous compound of 2-aminoethylphosphonate. Phylogenetic analysis based on 16S rRNA gene sequences showed that the strain belonged to the genus , with the highest similarity to 40Bstr34 (98.7 %).

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  • Cold-active bacteriophages, which are viruses that infect bacteria at low temperatures (≤4 °C), were isolated from sediment cores in the western Arctic Ocean, particularly phages ACA1 and ACA2, which thrive at just 1 °C.* -
  • These phages display typical myovirus features and have nearly identical genome sizes of about 36,825-36,826 bp, indicating a shared gene content and the presence of temperate phage characteristics that may aid in their survival.* -
  • The study reveals that even though they infect distinct bacterial hosts, the lack of cross-infection is likely due to significant genetic divergence and highlights the previously unexplored diversity of P2-like phages in polar environments
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Background: An unscheduled return visit (URV) to the emergency department (ED) within 72-h is an indicator of ED performance. An unscheduled return revisit (URV) within 72-h was used to monitor adverse events and medical errors in a hospital quality improvement program. The study explores the potential factors that contribute to URV to the ED within 72-h and the unscheduled return revisit admission (URVA) in adults below 50 years old.

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  • * Researchers performed a genomic analysis on 37 E. coli ST410 strains from companion animals, identifying key genetic features related to antibiotic resistance and virulence.
  • * The findings highlight the need for integrated health strategies, known as "One Health," to address the potential risks associated with these resistant bacteria in both animals and humans.
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A Gram-stain-negative, facultatively anaerobic, non-motile, rod-shaped bacterial strain, designated HL-MP18, was isolated from Arctic seawater after a prolonged incubation employing polypropylene as the sole carbon source. Phylogenetic analyses of the 16S rRNA gene sequence revealed that strain HL-MP18 was affiliated to the genus with close relatives LXJ103 (96.8 %) and KCTC 32327 (96.

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  • * A study of 27 wounds revealed that 81.48% completely healed with CAMP treatment, showing significant improvements in healing rate and wound size within the first three weeks.
  • * CAMP therapy was well-tolerated, with only mild side effects, suggesting it could be an effective adjunct treatment for various types of wounds in small animals.
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ΦGT1 is a lytic podovirus of an alphaproteobacterial species, with few closely matching sequences among characterized phages, thus defying a useful description by simple sequence clustering methods. The history of the ΦGT1 core structure module was reconstructed using timetrees, including numerous related prospective prophages, to flesh out the evolutionary lineages spanning from the origin of the ejectosomal podovirus >3.2 Gya to the present genes of ΦGT1 and its closest relatives.

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This study empirically analyzes the role of coaching leadership in enhancing an organization's creative performance, discussing and evaluating important mediating paths of coaching leadership regarding creative performance. As a result of an empirical analysis based on survey data collected from 332 employees of Korean companies, this study first confirms that coaching leadership has a positive effect on both employees' creative performance. We also found that psychological empowerment and constructive voice behavior positively mediated the relationship between coaching leadership and creative performance.

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