Exposure/Risk Assessment of Employees in Gasoline Refueling Stations with and Without the Efficacy of Vapor Recovery Systems in Mexico.

Concerns regarding the health risks associated with employe exposure to volatile chemicals during gasoline refueling necessitates rigorous investigation and effective countermeasures. This study aims to evaluate the efficacy of vapor recovery systems in mitigating exposure risks during gasoline refueling. Employee exposure to volatile organic compounds, aldehydes, carbon monoxide, and fine particulate matter (PM) was assessed at gasoline stations with and without vapor recovery systems.

Palliative care in the public health system: how do physicians deal with their patients at the end of life?

Background: Patients with cancer are referred late to palliative care services (PCS).

Aim: To analyse the time of referral to PCSs and the characteristics of patients that are referred.

Methods: A retrospective cohort.

Knowledge About Basic Life Support Among University Students.

Background:  Basic life support (BLS) is an essential skill set for responding to emergencies like cardiac arrest. However, the level of preparedness and interest in BLS among university students remains underexplored, especially in nonmedical populations.

Methods:  This study surveyed 427 University of Beira Interior (UBI) students to assess their knowledge, confidence, and interest in BLS training.

Transforming sludge into energy: impact of blend percentage on energy recovery potential and environmental benefits of co-combustion of wastewater sludge and coal in Brazil.

Proper waste management and sustainable energy production are crucial for human development. For this purpose, this study evaluates the impact of blending percentage on energy recovery potential and environmental benefits of co-combustion of wastewater sludge and Brazilian low-rank coal. The sludge and coal were characterised in terms of their potential as fuel and co-combustion tests were carried out in a pilot-scale bubbling fluidised bed focused on the influence of the percentage of sludge mixture on the behaviour of co-combustion with coal in terms of flue gas composition and fluidised bed temperature stability.

Bioinformatics and molecular biology tools for diagnosis, prevention, treatment and prognosis of COVID-19.

Since December 2019, a new form of Severe Acute Respiratory Syndrome (SARS) has emerged worldwide, caused by SARS coronavirus 2 (SARS-CoV-2). This disease was called COVID-19 and was declared a pandemic by the World Health Organization in March 2020. Symptoms can vary from a common cold to severe pneumonia, hypoxemia, respiratory distress, and death.

Insecticidal effects of Sargassum vulgare and Caulerpa racemosa extracts on Aedes aegypti.

Dengue is a viral disease present in many regions of the world. Aedes aegypti transmits it, and the most effective way to eliminate the mosquito is during the larval stage. Seaweeds possess metabolites with insecticidal properties, making them potential sources of new larvicides and viable alternatives to synthetic products used to control insect vectors of diseases.

Shaping current European mitochondrial haplogroup frequency in response to infection: the case of SARS-CoV-2 severity.

The frequency of mitochondrial DNA haplogroups (mtDNA-HG) in humans is known to be shaped by migration and repopulation. Mounting evidence indicates that mtDNA-HG are not phenotypically neutral, and selection may contribute to its distribution. Haplogroup H, the most abundant in Europe, improved survival in sepsis.

Tropical forest clearance impacts biodiversity and function, whereas logging changes structure.

The impacts of degradation and deforestation on tropical forests are poorly understood, particularly at landscape scales. We present an extensive ecosystem analysis of the impacts of logging and conversion of tropical forest to oil palm from a large-scale study in Borneo, synthesizing responses from 82 variables categorized into four ecological levels spanning a broad suite of ecosystem properties: (i) structure and environment, (ii) species traits, (iii) biodiversity, and (iv) ecosystem functions. Responses were highly heterogeneous and often complex and nonlinear.

Isolated Ophthalmoplegia: An Uncommon Presentation of Anti-glutamic Acid Decarboxylase 65 (Anti-GAD65) Neurological Syndrome.

Isolated ophthalmoplegia as an anti-glutamic acid decarboxylase 65 (anti-GAD65) antibody-associated neurological syndrome is rare. We present a case of a 22-year-old pregnant Hispanic female patient who presented initially with a left oculomotor nerve palsy following an emergency department (ED) visit for migraine headache. Brain imaging was done with no important findings.

Survival benefit associated with liver transplantation for hepatocellular carcinoma based on tumor burden scores at listing.

Introduction: Liver transplantation (LT) provides significant survival benefits to patients with unresectable HCC. In the United States, organ allocation policies for HCCs within the United Network for Organ Sharing criteria do not prioritize patients based on their differences in oncological characteristics. This study assessed whether transplant-associated survival benefits (TASBs) vary among patients with different tumor burden scores (TBS) measured at the time of listing.

Analysis of the Antibiotic-Potentiating Activity, Absorption, Distribution, Metabolism, and Excretion (ADME) and the Molecular Docking Properties of Phytol Against Multi-Drug-Resistant (MDR) Strains.

Phytol is a diterpene from the long-chain unsaturated acyclic alcohols, known for its diverse biological effects, including antimicrobial and anti-inflammatory activities. Present in essential oils, phytol is a promising candidate for various applications in the pharmaceutical and biotechnological sectors. This study aimed to evaluate the antibacterial and drug-potentiating effects of phytol against multidrug-resistant bacteria and to evaluate its properties: ADME and molecular docking.

Home high-flow therapy during recovery from severe chronic obstructive pulmonary disease (COPD) exacerbation: a mixed-methods feasibility randomised control trial.

Introduction: Patients recovering from severe acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have a 30-day readmission rate of 20%. This study evaluated the feasibility of conducting a randomised controlled trial to evaluate clinical, patient-reported and physiological effects of home high-flow therapy (HFT) in addition to usual medical therapy, in eucapnic patients recovering from AECOPD to support the design of a phase 3 trial.

Methods: A mixed-methods feasibility randomised controlled trial (quantitative primacy, concurrently embedded qualitative evaluation) (ISRCTN15949009) recruiting consecutive non-obese patients hospitalised with AECOPD not requiring acute non-invasive ventilation.

Evolving Impact of COVID-19 on Intestinal Transplant Recipients: A Single-Center Experience.

Background: There has been significant concern about coronavirus disease 2019 (COVID-19) among transplant recipients, particularly those who are highly immunosuppressed. Several studies have analyzed the impact of COVID-19 on different solid organ transplant patients. However, few isolated case reports of COVID-19 in intestinal and multivisceral transplant (ITx and MVTx) recipients are available in the literature.

Salivary oxytocin and amygdalar alterations in functional neurological disorders.

Individuals diagnosed with functional neurological disorder experience abnormal movement, gait, sensory processing or functional seizures, for which research into the pathophysiology identified psychosocial contributing factors as well as promising biomarkers. Recent pilot studies suggested that (epi-)genetic variants may act as vulnerability factors, for example, on the oxytocin pathway. This study set out to explore endogenous oxytocin hormone levels in saliva in a cohort of 59 functional neurological disorder patients and 65 healthy controls comparable in sex and age.

SARS-CoV-2 Spike S1 subunit triggers pericyte and microvascular dysfunction in human pancreatic islets.

The COVID-19 pandemic has profoundly affected human health, yet the mechanisms underlying its impact on metabolic and vascular systems remain incompletely understood. Clinical evidence suggests that SARS-CoV-2 directly disrupts vascular homeostasis, with perfusion abnormalities observed in various tissues. The pancreatic islet, a key endocrine mini-organ reliant on its microvasculature for optimal function, may be particularly vulnerable.

Performance of the VITEK® MS system for the identification of filamentous fungi in a microbiological laboratory in Chile.

Filamentous fungi are an emergent cause of severe infections in immunocompromised patients. Timely and accurate identification is crucial to initiate appropriate therapy. Traditional identification methods are time-consuming, labor-intensive, and operator-dependent.

Articulatory-kinematic changes in speech following surgical treatment for oral or oropharyngeal cancer: A systematic review.

Background: Treatment for oral or oropharyngeal squamous cell carcinoma (O&OSCC) often leads to problems with speech articulation. Articulatory-kinematic data may be especially informative in designing new therapeutic approaches for individuals treated for these tumours.

Aims: To provide a systematic review of the literature assessing the articulatory-kinematic consequences of oral and oropharyngeal cancer treatment.

Neonatal Clinical Assessment of the Puppy and Kitten: How to Identify Newborns at Risk?

Neonatal puppies and kittens have physiological and anatomical characteristics that differ from those of adult animals, which impacts the interpretation of physical examination and complementary tests. The veterinarian must be familiar with the clinical, laboratory, and imaging aspects observed in neonates. It is necessary to thoroughly evaluate the litter and the mother to notice the most subtle signs of illness and advise the owner to constantly monitor the newborns, quickly sending them to specialized care.

RhlR-mediated cooperation in cystic fibrosis-adapted isolates of .

uses quorum sensing (QS) to regulate the expression of dozens of genes, many of which encode shared products, called "public goods." possesses two complete acyl-homoserine lactone (AHL) QS circuits: the LasR-I and RhlR-I systems. Canonically, these systems are hierarchically organized: RhlR-I activity depends on LasR-I activation.

Identification of a tetrahedral apical cell preserved within a fossilized fern fiddlehead.

The gradual unfurling of fronds from tightly coiled tips, termed fiddleheads or croziers, is one of the most recognizable features of the fern lineage, but its evolutionary origin remains unclear. Here, we identify that fiddleheads and their development, termed circinate vernation, are not ubiquitous across ferns. Instead, they are a synapomorphy of a clade we term the circinatophytes that includes extant marattioid and leptosporangiate ferns.

The single-cell spatial landscape of stage III colorectal cancers.

We conducted a spatial analysis using imaging mass cytometry applied to stage III colorectal adenocarcinomas. This study used multiplexed markers to distinguish individual cells and their spatial organization from 52 colorectal cancers. We determined the landscape features of cellular spatial features in the CRC tumor microenvironment.