Publications by authors named "CORRIOL J"
Pyridoxylase at a concentration of 0.6 mmol/kg body weight injected intraperitoneally in rats, increased the resistance of animals to severe hypoxia (O2:3.2%; N2; 96.
View Article and Find Full Text PDFFive dogs and twelve rabbits were submitted to simulated diving at 6 ATA (compressed air) and 13-15 ATA (normoxic oxygen + nitrogen). Progressive decompressions were carried on for the first, rapid for the lasts. Motor nerve conduction velocity and nerve-muscle delays were measured.
View Article and Find Full Text PDF[Evaluation by electrocorticogram of the protective action of piridoxilate against cerebral hypoxia in rats].
C R Seances Soc Biol Fil
October 1977
Piridoxilate, at the concentration of 120 mg/kg i.p. in rats, enhanced resistance of these animals to hypoxia (N2 : O2 3,2 %).
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- The study analyzed EEG patterns in 90 professional divers, finding that 41% exhibited abnormal EEG readings that could be deemed unsuitable for diving.
- Despite being in good health, these EEG signs raise questions about their significance in relation to existing literature on diving fitness.
- The authors propose a categorization system for divers into three groups (fit, unfit, and questionable) and offer specific EEG criteria for determining diving fitness or unfitness.
It was shown that oxygen at high pressure (OHP) induced epileptic seizures and pulmonary damages on mice. Dipropylacetate protected mice against nervous syndrome better than did dipropylacetamide. No significant pulmonary protection was observed with both drugs.
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- The study found that the uptake of radioactive l-phenylalanine and l-tyrosine in rat brain tissue follows saturation kinetics, with specific saturation points (K(m)) of 0.86mm for l-phenylalanine and 1.64mm for l-tyrosine.
- The maximum rate of uptake (V(max.)) was determined to be 0.64 and 0.98 mumol/min per ml of tissue water for l-phenylalanine and l-tyrosine, respectively.
- The uptake process was hindered by factors such as lack of oxygen, cold temperature, and presence of metabolic inhibitors, indicating that these amino acids are actively transported.
The kinetics of the influx and efflux of radioactive l-glycine was studied in slices of rat cerebral cortex. The influx showed saturation kinetics and was inhibited by l-alanine. Influx was dependent on the presence of Na(+) ions and a metabolizable substrate.
View Article and Find Full Text PDF[Active storage of tryptophan in the isolated rat cerebral cortex].
C R Seances Soc Biol Fil
September 1970
The incubation of slices of cerebral cortex under hyperbaric oxygen pressures from 1 to 10 atmospheres in the presence of radioactive glucose, pyruvate, succinate, fumarate, L-glutamate, and gamma-aminobutyric acid causes a marked diminution of tissue oxidative reactions. There is a simultaneous decrease in phosphocreatine and adenosine triphosphate, and a reduction of the apparent intracellular ionic gradients. The increase of lipid peroxides, measured directly, is attributed to the toxic effects of hyperbaric oxygen.
View Article and Find Full Text PDFBy the use of 1mm-iodoacetate to inhibit glycolysis in guinea-pig cerebral tissue slices, the kinetics of the uptake of monosaccharides on transfer of tissue from 0 degrees to 37 degrees were studied. d-Ribose, d-galactose, d-mannose, l-sorbose, and d-fructose showed diffusion kinetics, whereas 2-deoxy-d-glucose, d-glucose, d-arabinose and d-xylose showed saturation kinetics.
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