[Recommendations for clinical practice: Prevention and management of varicella zoster virus (VZV) infection during pregnancy and the perinatal period (extended version)].

The Société de Pathologie Infectieuse de Langue Française released in 2024 a new national recommendation for clinical practice on the prevention and management of varicella zoster virus (VZV) infection during pregnancy and the perinatal period. The previous recommendation was issued in 1998, at a time of anti-VZV immunoglobulins shortage; it has hence become obsolete. This recommendation is a formalized expert consensus focusing on infectious diseases management; it is drawn up by a multidisciplinary working group (infectiologists, obstetricians, pediatricians, microbiologists, midwives, hygienists).

Circulating large extracellular vesicles as diagnostic biomarkers of indeterminate thyroid nodules: multi-platform omics analysis.

Background: While most thyroid nodules are benign, 7-15% are malignant. Patients with indeterminate thyroid nodules (specifically Bethesda IV/Thy3f) often undergo diagnostic hemithyroidectomy to reach a diagnosis on final histology. The aim of this study was to assess the feasibility of circulating large extracellular vesicles as diagnostic biomarkers in patients presenting with Thy3f thyroid nodules.

Wound Healing After Vaginal Delivery, Episiotomy, and Cesarean Section Delivery Among Women With IBD: Results From the PIANO Registry.

Background: Women with inflammatory bowel disease (IBD) face complexities of disease management during pregnancy and childbirth. Apprehension regarding vaginal delivery in pregnant individuals with IBD persists due to concern for perianal disease and perineal trauma. The incidence of poor wound healing after obstetric anal sphincter injury is approximately 4% in the general population.

COVID-19 Vaccinations, Infections, and Outcomes Among 784 People Living with HIV.

Introduction: Variants of COVID-19 are responsible for 700 million infections and 7 million deaths worldwide. Vaccinations have high efficiency in preventing infection and secondary benefits of reducing COVID-19 hospital admissions, attenuating disease severity and duration of illness. Conflicting reports were published regarding COVID-19 among PLWH.

Communications needs of family caregivers of geriatric unit residents at end-of-life.

Background And Objective: There is a dearth of literature regarding the communication needs of family caregivers of institutionalized older adults and the degree to which these needs are fulfilled. This study aimed to clarify those needs regarding communication with staff in geriatric facilities during older non-communicative residents' end-of-life.

Research Design And Methods: Personal interviews were conducted with 135 family caregivers from two geriatric medical centers and two nursing homes in Israel.

Determination of Molecular Ground State via Short Square Pulses on Superconducting Qubits.

Quantum computing is currently hindered by hardware noise. We present a freestyle superconducting pulse optimization method, incorporating two-qubit channels, that enhances flexibility, execution speed, and noise resilience. A minimal 0.

Emotion, attention and stress regulation as markers of resilience in male and female Israeli soldiers during the Israel-Hamas war.

Psychological resilience is a key factor for societal and military stability when faced with terror attacks and/or war. The research presents physiological findings-obtained with the electrodermal activity (EDA) and Auditory Sustained Attention Test (ASAT)-on stress responses, attentional and emotion regulation abilities in 57 Israel Defense Force male and female combat soldiers during the ongoing Israel-Hamas war. In addition, it shows self-reported resilience scores and post traumatic symptomatology measured by questionnaires and explores the relationship between the subjective and objective data.

H-SVEST: Validation and Adaptation of the Hebrew Version of the Second Victim Experience and Support Tool.

Background: Adverse medical events not only harm patients and families, but also have a significant negative impact on healthcare providers, with the potential to compromise future professional functioning. These "second victims" may need organizational support and rehabilitation to return to functionality.

Objectives: We analyzed the validity of an adapted tool, the Second Victim Experience and Support Tool (SVEST), on a population in Israel, H-SVEST.

Central mechanisms of muscle tone regulation: implications for pain and performance.

Muscle tone represents a foundational property of the motor system with the potential to impact musculoskeletal pain and motor performance. Muscle tone is involuntary, dynamically adaptive, interconnected across the body, sensitive to postural demands, and distinct from voluntary control. Research has historically focused on pathological tone, peripheral regulation, and contributions from passive tissues, without consideration of the neural regulation of active tone and its consequences, particularly for neurologically healthy individuals.

Absence of High-Pressure Ground-State Reentrant Ferroelectricity in PbTiO_{3}.

We study ferroelectricity in the classic perovskite ferroelectric PbTiO_{3} to high pressures with density functional theory (DFT) and experimental diamond-anvil techniques. We use second harmonic generation spectroscopy to detect lack of inversion symmetry. Consistent with early understanding and experiments, we find that ferroelectricity disappears at moderate pressures.

Drillers and bulldozer operators have experienced exceptionally high exposures to respirable crystalline silica in US surface coal mines.

Introduction: Previous studies suggest respirable crystalline silica (RCS) is an important driver of resurgent pneumoconiosis among US coal miners. Although greater attention has been focused on dust exposures in underground coal miners, surface miners are also at risk of severe disease. This study explores RCS exposure in this population.

[A 2024 inventory in oncology news].

The editorial board of the Bulletin du cancer has compiled a summary of the news from 2024 in oncology, based on the main results presented at international congresses or published over the past year. After a year marked by the success of the Olympic Games, the selection of data is presented and discussed in podiums of three main results by topic. Emphasis is placed on studies that have an immediate impact on practice and on data that raise important questions for the year 2025.

Comparative perceptions of sexual harassment among athletes across different competitive levels.

Purpose: Despite evidence that sports arenas are grooming ground for sexual harassment, consensus is still lacking what this term constitutes. The aim of this study is to examine how athletes of different levels and non-athletes perceive sexual harassment in sports through the lens of the Institutional Theory.

Method: Hundred and thirty pre-service physical education teachers (competitive and non-competitive athletes) and 53 Olympic athletes, rated 27 items divided into four levels of sexual harassment regarding men coaches' behaviors towards women athletes, on a scale of 1 (does not constitute sexual harassment) to 4 (constitutes sexual harassment to a great extent).

Induction triplet chemotherapy in patients with rectal adenocarcinoma and synchronous metastases, an AGEO-FFCD study.

Aim Of The Study: The management of synchronous metastatic rectal cancer (SMRC) is complex and multimodal, involving chemotherapy, surgery and/or radiotherapy. The aim of this study was firstly to confirm the efficacy of the induction FOLFIRINOX, and secondly to evaluate the different therapeutic strategies and outcomes of patients.

Patients And Methods: This French study combined data from a prospective FFCD trial and a multicenter cohort.

Preventing Severe COVID-19 with Tixagevimab-Cilgavimab in Hematological Patients Treated with Anti-CD20 Monoclonal Antibodies: An International Multicenter Study.

Introduction: Despite the declining public health emergency status, COVID-19 still poses significant risks, especially for immunocompromised individuals. We aimed to evaluate the effectiveness of tixagevimab-cilgavimab (T-C) prophylaxis in preventing severe COVID-19 in patients with hematologic malignancies (HM) treated with anti-CD20 therapy during the early Omicron variant phase of the pandemic.

Methods: The European Society of Clinical Microbiology and Infectious Diseases Study Group for Respiratory Viruses (ESGREV) conducted a multicenter retrospective cohort study involving 15 centers from 5 countries.

Distribution of the genus Dendrocephalus (Crustacea, Branchiopoda, Anostraca) in Argentina: a review.

The fairy shrimp Dendrocephalus brasiliensis was first found in Brazil in temporary rainpools in the northeastern states of Piauí and Bahia. Gradually, new records were added in other northeastern states up to the state of Minas Gerais, in the Southeast region of the country. The species was even found south of Minas Gerais in the state of São Paulo, but not in wild conditions, but in rearing tanks associated with aquaculture practices.

Reassessing the need for scheduled replacement of short term central venous catheters: A narrative comprehensive review.

Central venous catheters (CVCs) are essential in modern healthcare but are associated with significant risks, particularly catheter-related bloodstream infections (CRBSIs). Current guidelines do not recommend routine replacement of CVCs based on time alone. However, recent evidence challenges this recommendation.

Trial eligibility, treatment patterns and outcome for venetoclax-based therapy in AML: a prospective cohort study.

Venetoclax (Ven) plus hypomethylating agents are considered standard-of-care for patients with acute myeloid leukemia (AML) judged ineligible for intensive chemotherapy (IC). Real-world studies complement clinical trials, since patterns of patient selection, treatment-exposure and post-remission management may vary. This prospective observational multi-center study included 209 newly diagnosed IC-ineligible patients with a median age 75 years (interquartile range, 71-81 years).

Non- Tuberculous mycobacterial infection and pulmonary disease In Northern Israel: a focus on M. simiae.

Background: The prevalence of non-Tuberculous Mycobacteria pulmonary disease (NTM-pd) is rising globally. Previously, we described a high prevalence of M. simiae isolation in Israel.

Use of Multimodal Imaging for Diagnosis and Management of Pulmonary Artery Sarcoma Mimicking as Acute Pulmonary Embolism.

Pulmonary artery sarcoma is a rare intravascular tumor that mimics pulmonary embolus. Early recognition and referral to surgery is important because nonsurgically treated tumors have a poor prognosis. Here, we describe a case of pulmonary artery sarcoma diagnosed with multimodal imaging, which also aided in surgical planning.

Outcomes Following Treatment for Progression in Patients Treated With Durvalumab Consolidation in LA-NSCLC.

Introduction: PACIFIC established consolidative durvalumab for LA-NSCLC, but only about half of patients completed a year of therapy. Data on treatment patterns and outcomes after durvalumab are limited.

Methods: Our analysis included patients from a US nationwide database with LA-NSCLC who received consolidative durvalumab between 2017 and 2023 and had subsequent systemic therapy, classified as PD-L1 monotherapy, PD-L1+chemotherapy, chemotherapy alone, PD-L1+CTLA4, or targeted therapy (TT).

Effect of transcranial direct current stimulation with cognitive training on executive functions in healthy older adults: a secondary analysis from the ACT trial.

Cognitive aging has become a public health concern as the mean age of the population is ever-increasing. It is a naturalistic and common process of degenerative and compensatory changes that may result in neurocognitive disorders. While heterogeneous, cognitive aging mostly affects executive functions that may be associated with functional losses during activities of daily living.