Is videoconference pulmonary rehabilitation associated with improvements in knowledge in people living with COPD? A propensity-matched service-evaluation.

Pulmonary rehabilitation (PR) services are increasingly using alternative programme delivery modes, for example telerehabilitation strategies including videoconferencing, to improve patient choice and accessibility. Although telerehabilitation results in improvements in core outcomes, the effect on knowledge attainment is not known. To observe the real-world responses of patients choosing to undergo videoconference PR to a matched control group choosing to undergo in-person PR, in terms of knowledge attainment.

adapted to steppe-desert climate extremes one million years ago.

Questions about when early members of the genus adapted to extreme environments like deserts and rainforests have traditionally focused on . Here, we present multidisciplinary evidence from Engaji Nanyori in Tanzania's Oldupai Gorge, revealing that thrived in hyperarid landscapes one million years ago. Using biogeochemical analyses, precise chronometric dating, palaeoclimate simulations, biome modeling, fire history reconstructions, palaeobotanical studies, faunal assemblages, and archeological evidence, we reconstruct an environment dominated by semidesert shrubland.

Chemisorption and physisorption of alcohols on iron(III) oxide-terminated surfaces from nonpolar solvents.

Hypothesis: The adsorption isotherm of alkanols at the haematite|hydrocarbon interface should reflect both chemisorption (chemically bonded fraction) and physisorption (hydrogen bonded fraction).

Experiments And Model: Quartz crystal microbalance (QCM) and X-ray photoelectron spectroscopy (XPS) have been used for characterization of FeO|hydrocarbon interfaces with absorbed alcohol. A range of FeO-terminated surfaces, alkanols, hydrocarbons and temperatures have been investigated.

Pain and Dyspnea During Acute Exacerbations of Chronic Obstructive Pulmonary Disease: Documentation Audit 2019-2020.

Patient-reported outcome measures (PROMs) assess the severity and impact of both pain and dyspnea in those with acute exacerbations of chronic obstructive pulmonary disease (COPD), but their frequency of use in clinical practice is unknown. This study aimed to determine the point prevalence of pain and dyspnea assessment in patients hospitalized with an acute exacerbation of COPD and the measurement tools applied for this purpose in clinical practice. Clinical notes and observation charts of patients admitted with acute exacerbations of COPD to a metropolitan hospital in 2019 and 2020 were retrospectively audited to identify the point prevalence of pain and dyspnea assessment, the PROMs applied, and their associated focal periods.

An Open-Source Algorithm for Correcting Stress Wave Dispersion in Split-Hopkinson Pressure Bar Experiments.

Stress wave dispersion can result in the loss or distortion of critical high-frequency data during high-strain-rate material tests or blast loading experiments. The purpose of this work is to demonstrate the benefits of correcting stress wave dispersion in split-Hopkinson pressure bar experiments under various testing situations. To do this, an innovative computational algorithm, SHPB_Processing.

Helicopter emergency medical services demonstrate reduced time to emergency anaesthesia in an undifferentiated trauma population: a retrospective observational analysis across three major trauma networks.

Background: Early rapid sequence induction of anaesthesia (RSI) and tracheal intubation for patients with airway or ventilatory compromise following major trauma is recommended, with guidance suggesting a 45-min timeframe. Whilst on-scene RSI is recommended, the potential time benefit offered by Helicopter Emergency Medical Services (HEMS) has not been studied. We compared the time from 999/112 emergency call to delivery of RSI between patients intubated either in the Emergency Department or pre-hospital by HEMS.

The role of virtual wards in maternity in the United Kingdom.

Virtual wards are an initiative which aims to provide hospital care from the comfort of the patient's own home. Monitoring and additional services, such as intravenous drugs and fluids and blood tests can be undertaken through this system. Although virtual wards have been used in the UK since 2005 in specialties such as General Medicine, General Surgery and Paediatrics, their use in maternity has been more limited.

Five Year Outcomes in Low-Risk Patients Undergoing Surgery in the PARTNER 3 Trial.

Background: Surgery remains an important treatment for low-risk patients with severe symptomatic aortic stenosis (AS). We evaluated 5-year outcomes in low-risk patients undergoing isolated surgical aortic valve replacement (SAVR) or SAVR with concomitant procedures within the randomized PARTNER 3 trial.

Methods: In the PARTNER 3 trial, 454 patients underwent surgery for severe, symptomatic, tri-leaflet AS and were followed for 5 years.

Invasive Species, Health, and Global History Afterword: The Disavowal of Human Agency.

The papers in this special issue explore the metaphorical realms that inform discourses on disruptive plants and animals. They explore how species movements in the twentieth century were framed and interpreted, and the medical, scientific, legal, and bureaucratic processes that turned a non-native or mobile species into a formally designated "invasive" one. In doing so, they allow insight into the mechanisms of disavowal, how some species were constructed as the cause of disease and ecological change, while others escaped censure.

New York State Climate Impacts Assessment Chapter 04: Buildings.

New York State has nearly 5.3 million buildings, and all of them are vulnerable in some way to the impacts of climate change. Understanding these impacts is critical, because risks to buildings not only threaten individual lives but also pose threats to community-level resilience.

A horizon scan of biological conservation issues for 2025.

We discuss the outcomes of our 16th horizon scan of issues that are novel or represent a considerable step-change and have the potential to substantially affect conservation of biological diversity in the coming decade. From an initial 96 topics, our international panel of 32 scientists and practitioners prioritised 15 issues. Technological advances are prominent, including metal and non-metal organic frameworks, deriving rare earth elements from macroalgae, synthetic gene drives in plants, and low-emission cement.

Correction: Comprehensive Profiling of Plasma Fatty Acid Concentrations in Young Healthy Canadian Adults.

[This corrects the article DOI: 10.1371/journal.pone.

Guideline recommended statin eligibility and use among U.S. adults ages 20 to 39 years.

Objective: Guidelines for statin therapy emphasize treatment of adults ages 40-75 years, with less guidance for the treatment of younger adults, ages 20-39 years. Only two class 1 recommendations for statin apply to younger adults: 1) secondary prevention and 2) severe hypercholesterolemia (LDL-C ≥ 190 mg/dL). The implementation of guidelines within this age group has not been well studied.

MuscleMap: An Open-Source, Community-Supported Consortium for Whole-Body Quantitative MRI of Muscle.

Disorders affecting the neurological and musculoskeletal systems represent international health priorities. A significant impediment to progress in trials of new therapies is the absence of responsive, objective, and valid outcome measures sensitive to early disease changes. A key finding in individuals with neuromuscular and musculoskeletal disorders is the compositional changes to muscles, evinced by the expression of fatty infiltrates.

Contrasting Magnetic Structures in the Quaternary Sulfides BaFeMS (M = Sb, Bi).

BaFeSbS and BaFeBiS are two isostructural quaternary sulfides that crystallize in the space group with four formula units per unit cell. BaFeSbS has lattice parameters = 12.08609(3) Å, = 8.

3D-printing of dipyridamole/thermoplastic polyurethane materials for bone regeneration.

Tissue engineering combines biology and engineering to develop constructs for repairing or replacing damaged tissues. Over the last few years, this field has seen significant advancements, particularly in bone tissue engineering. 3D printing has revolutionised this field, allowing the fabrication of patient- or defect-specific scaffolds to enhance bone regeneration, thus providing a personalised approach that offers unique control over the shape, size, and structure of 3D-printed constructs.

Misaligned hope and conviction in health care.

It is often said that it is important for patients to possess hope that their treatment will be successful. We agree, but a widely appealed to type of hope-hope based on conviction (religious or otherwise), renders this assertion problematic. If conviction-based hope influences patient decisions to undergo medical procedures, then questions are raised about the scope of patient autonomy.

Durvalumab Versus Chemotherapy as First-line Treatment for Metastatic NSCLC With Tumor PD-L1 Expression of 25% or Higher: Results From the Randomized Phase 3 PEARL Study.

Introduction: PEARL (NCT03003962) is an open-label, phase 3 study comparing first-line durvalumab monotherapy with chemotherapy in patients with metastatic NSCLC (mNSCLC [EGFR/ALK wild type]) with programmed cell death ligand 1 (PD-L1) tumor cell (TC) membrane expression status of 25% or higher. We report the final analysis of PEARL.

Methods: Adults (N = 669) with previously untreated stage IV mNSCLC were randomized (1:1) to durvalumab 20 mg/kg every four weeks or chemotherapy every three weeks for four to six cycles.

Caregiver experiences of oral feeding in infants on long-term high flow nasal cannula support.

Purpose: Navigating the feeding journey of medically complex infants on long-term high flow nasal cannula support can be challenging for caregivers, especially given inconsistencies in clinical practice for oral feeding on high flow nasal cannula support. The aim of this study was to explore the perspectives of caregivers who have experienced this journey, to inform best practice care.

Method: This study used a generic qualitative inquiry approach.

DPYD genotype-guided dose personalisation for fluoropyrimidine-based chemotherapy prescribing in solid organ cancer patients in Australia: GeneScreen 5-FU study protocol.

Background: Fluoropyrimidine (FP) chemotherapies are commonly prescribed for upper and lower gastrointestinal, breast and head and neck malignancies. Over 16,000 people with cancer require FP chemotherapies per annum in Australia. Between 10 and 40% patients experience grade 3-4 (≥ G3) toxicities that require hospital-based management ± intensive care admission.

Evaluating a Kid's Dementia Awareness Game with Pre-Licensure Children and Young People's Nursing (CYP) Students in Northern Ireland - A Pre/Posttest Study.

Dementia not only affects the person living with the condition but also their family and wider social circle. For that reason, it is important to educate family members, the wider public and health professionals. How a child and young people's (CYP) nurse supports and responds to a CYP whose family member has dementia or acts as a carer is of interest to pre-licensure (pre-registration) CYP nursing programs.

Promising biomarker panel to monitor therapeutic efficacy of neoadjuvant chemotherapy in pancreatic cancer patients.

Background: Neoadjuvant chemotherapy (NAC) can provide improved survival outcomes in pancreatic ductal adenocarcinoma (PDAC) patients who respond to treatment, but currently available biomarkers cannot reliably predict NAC response. This study aimed to determine the potential of a previously identified diagnostic and prognostic biomarker panel (i.e.