Zoonosis: social and environmental connections in the Mexico-United States border region.

The emerging risks facing humanity have highlighted the need to address and prevent challenges through multilateral preventive strategies. The Mexico-United States (US) border is a region with great biological biodiversity and both countries shared a similar history and intense socioeconomic, and cultural interrelationships. Also, it has an extraordinary ecological contrast, resulting in an enormous biological diversity in a broad Nearctic-Neotropical transition zone.

Antinociceptive Potential of L. Bark Extract and Caffeic Acid: Insights into Pain Modulation Pathways.

This study evaluated the antinociceptive effect of the L. bark extract (HEXA) and its primary component, caffeic acid (CA), through in vivo assays. : The antinociceptive properties were assessed using abdominal writhing, hot plate, and Von Frey tests.

Nutritional Value of for Weaner Piglets.

This study evaluates the nutritional value of spray-dried biomass to infer its applicability for weaner piglet feeding. Twenty-four piglets were randomly allocated to four dietary treatments ( = 6) with increasing inclusion (0, 5, 10, and 15%) levels. After a 4-day adaptation period, the digestibility experiment lasted two weeks, with daily excreta collection.

Inflammatory discoveries two years after acute severe COVID-19: a longitudinal biomarker profile assessment in long COVID individuals in the Brazilian Amazon.

Background: In SARS-CoV-2 infection, cytokines and laboratory biomarkers play a key role in disease progression and their long-term levels have been associated with the outcome of long COVID-19.

Objectives: I) study the levels of cytokines, hematological and biochemical biomarkers in the acute and post-acute phases of COVID-19 disease; and II) assess the impact of COVID-19 vaccine doses on fatigue symptoms.

Methods: This study is an exploratory cohort nested within a clinical and laboratory follow-up of surviving participants after pre-vaccine acute COVID-19 infection with severe clinical manifestations.

Electronic band evolution between Lieb and kagome nanoribbons.

We investigate the electronic properties of nanoribbons made out of monolayer Lieb, transition, and kagome lattices using the tight-binding model with a generic Hamiltonian. It allows us to map the evolutionary stages of the interconvertibility process between Lieb and kagome nanoribbons by means of only one control parameter. Results for the energy spectra, the density of states, and spatial probability density distributions are discussed for nanoribbons with three types of edges: straight, bearded, and asymmetric.

Greater adherence to the Dietary Approaches to Stop Hypertension (DASH) diet during pregnancy reduces the likelihood of having a large-for-gestational-age newborn.

Background/objectives: Studies suggest that greater maternal adherence to the Dietary Approaches to Stop Hypertension (DASH) diet reduces the risk of both maternal and fetal adverse health outcomes. The study aimed to evaluate the relationship between adherence to the DASH diet during pregnancy and the classification of birth weight according to gestational age.

Subjects/methods: Secondary analysis of a prospective cohort of 601 mother and child pairs who attended primary healthcare in a Brazilian municipality.

Identifying Factors that Influence Pediatric Echo Lab Image Quality: Development and Validation of a New Assessment Tool.

No method of evaluating transthoracic echocardiograms (TTE) image quality (IQ) has been validated. Furthermore, structural echo lab elements impacting IQ are unknown. We sought to develop and validate a TTE IQ grading tool and determine patient and echo lab features associated with IQ.

Lung Adenocarcinoma and Peripheral Blood Eosinophilia.

There are many causes of peripheral blood eosinophilia (PBE), including allergic, infectious, rheumatic, and hematologic disorders. Solid tumor cancers, such as lung cancer, can also cause PBE, and although rare, being diagnosed with PBE in this way is associated with a worse prognosis than for lung cancer patients without PBE. Additionally, some cancer patients develop PBE when receiving treatment with immune checkpoint inhibitors (ICIs).

Planning Matters: A Document Analysis of 24 Portuguese Health Programmes.

Background: Health planning is essential for effective public health interventions and optimal resource utilisation. The Portuguese Directorate-General of Health has a long history of developing health plans and programmes, for communicable and noncommunicable diseases, and their determinants. This study aimed to review the current 24 programmes and assess the adequacy of their structure and content.

Influence of Host and Landscape-Associated Factors in the Infection and Transmission of Pathogens: The Case of Directly Transmitted Virus in Mammals.

Background: Among pathogens associated with mammals, numerous viruses with a direct transmission route impact human, domestic and wild species health. Host and landscape factors affect viral infection and transmission dynamics of these viruses, along with barriers to host dispersal and gene exchange. However, studies show biases toward certain locations, hosts and detected pathogens, with regional variations in similar host-virus associations.

Impact of Variants, Epidemiological Trends, and Comorbidities on Hospitalization Rates of Unvaccinated Children in Brazil: A Retrospective Study (2020-2022).

This retrospective study aimed to investigate the impact of the emergence of new variants and the epidemiological scenario on hospitalization rates of unvaccinated children (0-12 years) in Brazil. The study included 1614 children admitted to a hospital between March 2020 and December 2022 but 101 (6.3%) of them testing positive for COVID-19 via RT-PCR.

Assessment of Public Stigma, Mental Health Literacy, and Help-Seeking Intentions Based on Different Dimensions of Obsessive-Compulsive Content: A Study of the Spanish Mental Health-Naïve Population.

Background: Obsessive-compulsive (OC) disorder is a debilitating disorder with a high delay in help-seeking that could be associated with two barriers that may differ between OC content dimensions: public stigma and mental health literacy.

Objectives: We aim to describe and analyze the differences among OC content dimensions in public stigma, social distance desire, mental health literacy, and help-seeking intention in a sample of the mental health-naïve population.

Methods: A total of 487 participants from the Spanish community with no previous knowledge of or experience with OCD were randomly allocated one of six vignettes describing a person with OC symptoms of one out of six contents (i.

An alternate route for cellulose microfibril biosynthesis in plants.

Similar to cellulose synthases (CESAs), cellulose synthase-like D (CSLD) proteins synthesize β-1,4-glucan in plants. CSLDs are important for tip growth and cytokinesis, but it was unknown whether they form membrane complexes in vivo or produce microfibrillar cellulose. We produced viable CESA-deficient mutants of the moss to investigate CSLD function without interfering CESA activity.

Accessory Extraocular Muscle: A Rare Cause of Strabismus.

Accessory extraocular muscles are rare intraorbital congenital structures that can cause diplopia and restrictive strabismus.

Urine and serum-based ELISA using a recombinant protein and synthetic peptide for the diagnosis of tegumentary leishmaniasis.

The diagnosis of tegumentary leishmaniasis (TL) presents problems by the variable sensitivity and specificity of the tests, and the biological samples used are also invasive. Here, ELISA experiments were performed using paired TL patient urine and serum samples in reaction against the recombinant LiHyS protein, a predicted B cell epitope and parasite antigenic extract (SLA). Two hundred and five paired samples were used, which were provided by TL patients, healthy controls and patients with Chagas disease, leprosy, malaria or HIV-infected.

Assessing Antiparasitic Compounds Persistence in Cattle Hair by DART-MS.

This study introduces an alternative strategy for evaluating antiparasitic persistence compounds in cattle hair by Direct Analysis in Real Time Mass Spectrometry (DART-MS). The developed DART-MS method aimed to determine fenthion, chlorpyrifos, and cypermethrin in cattle hair samples. DART-MS analyses were performed in positive ion mode, and parameters related to the DART source were evaluated.

Chiral Propagation of Plasmon Polaritons due to Competing Anisotropies in a Twisted Photonic Heterostructure.

We theoretically demonstrate chiral propagation of plasmon polaritons and show that it is more efficient and easier to control than the recently observed chiral shear phonon polaritons. We consider plasmon polaritons created in an anisotropic two-dimensional (2D) material twisted with respect to an anisotropic substrate to best exploit the competition between anisotropic electron-electron interactions and the anisotropic electronic structure of the host material. Gate voltage and twist angle are then used for precise control of the chiral plasmon polaritons, overcoming the existing restrictions with chiral phonon polaritons.

The global issue of metal contamination in sharks, rays and skates and associated human health risks.

Elasmobranchs, including sharks, rays, and skates, are a global protein source but face threats from overfishing and population declines. Despite their lower market value, increased consumption raises sustainability and public health concerns. Commonly landed species like the Blue Shark, Shortfin Mako, and Spiny Dogfish are particularly vulnerable to bioaccumulation of metals such as mercury (Hg), lead (Pb), cadmium (Cd), and arsenic (As), posing health risks to consumers.

Antiviral Potential and Chemical Composition of Wild Spreng. Populations (Asteraceae) from Córdoba, Argentina: Perspective on Population Variability.

Medicinal plants have been explored worldwide as potential alternatives for the prevention and treatment of different diseases, including viral infections. Spreng. (Asteraceae) is a native medicinal species widely used in South America.

Ketogenesis protects against MASLD-MASH progression through mechanisms that extend beyond overall fat oxidation rate.

The progression of metabolic-dysfunction-associated steatotic liver disease (MASLD) to metabolic-dysfunction-associated steatohepatitis (MASH) involves complex alterations in both liver-autonomous and systemic metabolism that influence the liver's balance of fat accretion and disposal. Here, we quantify the relative contribution of hepatic oxidative pathways to liver injury in MASLD-MASH. Using NMR spectroscopy, UHPLC-MS, and GC-MS, we performed stable-isotope tracing and formal flux modeling to quantify hepatic oxidative fluxes in humans across the spectrum of MASLD-MASH, and in mouse models of impaired ketogenesis.

Association of sociodemographic, obstetric characteristics, lifestyle and food consumption with life satisfaction and optimism among overweight pregnant women.

The present study investigated the relationships between maternal characteristics and subjective well-being (life satisfaction and optimism) among overweight Brazilian adult pregnant women. A cross-sectional study utilising baseline data from a randomised controlled clinical trial was conducted. A total of 330 women were investigated.

Captopril inhibits the overproduction of proopiomelanocortin and adrenocorticotropic hormone in the pituitary gland of male diabetic mice in close relationship with an increase in glucocorticoid receptor expression.

Prior investigation shows that diabetic patients present hypothalamus-pituitary-adrenal (HPA) axis hyperactivity related to impaired negative feedback. This study investigates the effect of Captopril on the overproduction of adrenocorticotropic hormone (ACTH) and its precursor proopiomelanocortin (POMC) in the pituitary gland of male diabetic mice. Diabetes was induced by intravenous injection of alloxan into fasted Swiss-webster mice, and the animals were treated with Captopril for 14 consecutive days, starting 7 days post-diabetes induction.