Acceptability of the Fit2ThriveMB mHealth physical activity promotion intervention in women with metastatic breast cancer.

Purpose: Increasing physical activity (PA) is safe and associated with improved health outcomes in patients with metastatic breast cancer (MBC). Mobile health (mHealth) PA interventions that allow for remote monitoring and tailoring to abilities may be particularly useful for MBC patients. However, limited data exist on the acceptability of these interventions for MBC patients.

Effect of the Fit2Thrive Intervention on Patient-reported Outcomes in Breast Cancer Survivors: A Randomized Full Factorial Trial.

Background: Moderate to vigorous physical activity (MVPA) interventions improve patient-reported outcomes (PROs) of physical and psychological health among breast cancer survivors (BCS); however, the effects of specific intervention components on PROs are unknown.

Purpose: To use the Multiphase Optimization Strategy (MOST) to examine overall effects of the Fit2Thrive MVPA promotion intervention on PROs in BCS and explore whether there are intervention component-specific effects on PROs.

Methods: Physically inactive BCS [n = 269; Mage = 52.

A multi-site trial of an electronic health integrated physical activity promotion intervention in breast and endometrial cancers survivors: MyActivity study protocol.

Despite the known benefits of moderate-to-vigorous physical activity (MVPA) for breast and endometrial cancer survivors, most are insufficiently active, interventions response is heterogeneous, and MVPA programming integration into cancer care is limited. A stepped care approach, in which the least resource-intensive intervention is delivered first and additional components are added based on individual response, is one strategy to enhance uptake of physical activity programming. However, the most effective intervention augmentation strategies are unknown.

Dead molluscan shells from multiple trophic groups as archives of nitrogen isotopic evidence of wastewater gradients in estuaries.

Increased coastal urbanization worldwide has resulted in increased nitrogen inputs to ecosystems, leading to eutrophication and other negative effects. We assessed δN in the dead-collected shells of three molluscan species in two estuaries in order to evaluate their ability to identify known gradients in wastewater nitrogen input, namely from private septic systems feeding directly into Waquoit Bay and from a groundwater plume reflecting wastewater injection at a municipal treatment plant in West Falmouth Harbor, Massachusetts, USA. Shells of a suspension-feeder (Geukensia demissa), a micro-algal grazer (Littorina littorea), and an omnivore (Nassarius obsoletus) were collected from lower intertidal sediments near the taxon's life habitat.

An Ethical Risk Management Approach for Medical Devices.

Introduction: The Food and Drug Administration (FDA) audits and validates devices before mass production to ensure high standards, safety, and quality of medical devices being marketed. Despite those measures in place, consumers' trusts in medical devices are still dwindling based on safety and privacy risks that eventually influence the health of patients.

Methods: The method employed in this study is conceptual and includes a selection of a company that develops medical devices to use as an example organization to apply the hybrid risk management framework, defined herein in the results and discussion section.

Technology Use and Preferences for Minority Diabetes Self-Management Application.

We describe technology use and preferences of minority patients with diabetes who participated in focus groups in order to help design a mobile/online health application (or, app) to assist with diabetes self-management. Self-management apps should include health-related data and suggestions about food. The authors close by recommending additional considerations for future self-management mobile/online apps.

Shame, social deprivation, and the quality of the voice-hearing relationship.

Objectives: Many individuals hold different beliefs about the voices that they hear and have distinct relationships with them, the nature of which may determine the distress experienced. Understanding what factors contribute to these beliefs and relationships and consequently the resulting distress is important. The current research examined whether shame and social deprivation, in a sample of adult voice-hearers, were related to the relationships that individuals had with their voices or the beliefs that they held about them.

Shame and the psychosis continuum: A systematic review of the literature.

Objectives: Shame is increasingly implicated in the development and maintenance of several psychological problems including psychosis. The aim of the current paper was to review the research literature concerning the relationship between shame and the psychosis continuum, examining the nature and direction of this relationship.

Method: Systematic searches of databases PsycINFO, Medline, Scopus, and Web of Science (from the earliest available database date until November 2016) were undertaken to identify papers that examined the relationship between shame and psychosis or psychotic experiences.

Exacerbation of cardiac energetic impairment during exercise in hypertrophic cardiomyopathy: a potential mechanism for diastolic dysfunction.

Aims: Hypertrophic cardiomyopathy (HCM) is the commonest cause of sudden cardiac death in the young, with an excess of exercise-related deaths. The HCM sarcomere mutations increase the energy cost of contraction and impaired resting cardiac energetics has been documented by measurement of phosphocreatine/ATP (PCr/ATP) using (31)Phosphorus MR Spectroscopy ((31)P MRS). We hypothesized that cardiac energetics are further impaired acutely during exercise in HCM and that this would have important functional consequences.

Elusiveness of menstrual cycle effects on mate preferences: comment on Gildersleeve, Haselton, and Fales (2014).

This comment uses meta-analytic techniques to reconcile the apparent conflict between Gildersleeve, Haselton, and Fales's (2014) conclusion of "robust" effects of menstrual cycles on women's preferences for men of purported genetic quality and Wood, Kressel, Joshi, and Louie's (2014) assessment that the few, limited effects in this literature appear to be research artifacts. Despite these divergent conclusions, the literature in both reviews shows a broad distribution of effects, with fully one third of findings countering evolutionary psychology predictions. We demonstrate that Gildersleeve et al.

Effects of intrapartum stress on fetal adrenal function.

Objective: Our purpose was to characterize the fetal adrenal response to acute intrapartum stress in otherwise uncomplicated pregnancies.

Study Design: Term infants (n = 61) diagnosed as having fetal distress during labor, as indicated by heart rate abnormalities, and delivered of women having normal pregnancies were pair-matched with 61 infants showing no signs of fetal distress or acidemia (controls) on the basis of gestational age and delivery method. Umbilical cord serum dehydroepiandrosterone sulfate and cortisol were measured, and the data were analyzed by two-tailed t test, Fisher's exact test, analysis of variance, and Tukey's multiple range test.

Adrenocorticotropin interferes with transforming growth factor-beta-induced growth inhibition of neocortical cells from the human fetal adrenal gland.

The effects of transforming growth factor-beta (TGF-beta) and ACTH on growth, as indicated by [3H]thymidine incorporation into DNA, of primary cultures of neocortical cells from the human fetal adrenal gland were studied. TGF-beta inhibited, in a dose- and time-dependent manner, the growth of fetal neocortical cells, and ACTH significantly blunted the inhibitory effects of TGF-beta on growth of these cells. ACTH did not block the inhibitory effects of TGF-beta on growth of fetal adrenal fibroblasts or liver cells; neither ACTH nor TGF-beta had any effect on growth of fetal kidney cells.