Publications by authors named "C von Neuhoff"

Satellite cells take an indispensable place in skeletal muscle regeneration, maintenance, and growth. However, only limited works have investigated effects of dietary compounds on the proliferation of porcine satellite cells (PSCs) and related mechanisms. Sulforaphane (SFN) at multiple levels was applied to PSCs.

View Article and Find Full Text PDF

Pig production depends on a health and performance balance. An approach to improve intestinal health is the oregano essential oil (OEO) supplementation within a conventional diet. Intestinal integrity regulating effects, for example gene expression, of some feed ingredients are important key factors for that balance.

View Article and Find Full Text PDF
Article Synopsis
  • Inflammation is influenced by epigenetic modifications such as DNA methylation and histone acetylation, and the study explores how sulforaphane (SFN), an HDAC inhibitor, affects these processes during acute inflammation.
  • SFN was found to inhibit HDAC activity, promote histone acetylation, and induce DNA demethylation, leading to increased expression of immune-related genes after LPS stimulation in monocyte-derived dendritic cells.
  • The findings suggest that SFN's ability to regulate epigenetic changes may help control excessive inflammatory cytokine production, highlighting its potential as a protective and anti-inflammatory agent.
View Article and Find Full Text PDF

Transcription factors (TFs) are known to be involved in regulating the expression of several classes of genes during folliculogenesis. However, the regulatory role of TFs during oxidative stress (OS) is not fully understood. The current study was aimed to investigate the regulation of the TFs in bovine granulosa cells (bGCs) during exposure to OS induced by HO in vitro.

View Article and Find Full Text PDF

Epididymal sperm shows higher cryoresistance than ejaculated sperm. Although the sperm proteome seems to affect cell cryoresistance, studies aiming at identifying proteins involved in sperm freezing-tolerance are scarce. The aims of this study were to investigate differences of sperm freezability and proteome between epididymal and ejaculated sperm in three mountain ungulates: Iberian ibex, Mouflon and Chamois.

View Article and Find Full Text PDF