Publications by authors named "C von Grothusen"

Background: Mid-term comparative data for the self-expanding ACURATE neo2 transcatheter heart valve and the balloon-expandable SAPIEN 3 Ultra are lacking.

Objectives: The aim of this study was to compare 1-year outcomes after transcatheter aortic valve replacement of these 2 valves.

Methods: A total of 2,106 patients from 3 centers (neo2, n = 1,166; Ultra, n = 940) undergoing transfemoral transcatheter aortic valve replacement were analyzed retrospectively.

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Article Synopsis
  • Precise implantation depth is crucial for the success of transcatheter aortic valve replacement (TAVR), but the effects of incorrect depths on the ACURATE NEO2 prosthesis hadn't been previously studied.
  • A study of 1,839 patients evaluated outcomes based on three implantation depth categories: high (<3 mm), optimal (3-7 mm), and low (>7 mm), finding no significant differences in technical success or paravalvular regurgitation rates.
  • While higher implantation showed better hemodynamics, it also had a higher risk of embolization; low implantation led to more pacemaker needs, suggesting it's better to avoid high placements to minimize risks.
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Previous trials reported comparable results with PASCAL and earlier MitraClip generations. Limited comparative data exist for more contemporary MitraClip generations, particularly the large MitraClip XT(R/W). We aimed to evaluate acute and 30-day outcomes in patients undergoing mitral valve transcatheter edge-to-edge repair (M-TEER) with one of the large devices, either PASCAL P10 or MitraClip XT(R/W) (3rd/4th generation).

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Background: Challenging anatomies and comorbidities have impact on success in transcatheter aortic valve replacement (TAVR). There is controversy whether the extent of the aortic angle (AA) has an impact on procedural outcomes. Matched comparative outcome data of new generation transcatheter heart valves (THVs) in horizontal aorta (HA) are scarce.

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Background: Diabetic patients with coronary artery disease may benefit from elective coronary artery bypass graft (CABG) surgery. It is unknown whether this merit is transferable to patients with acute myocardial infarction (AMI) undergoing surgery.

Method: A total of 1,427 patients underwent CABG within 48 hours of being diagnosed with AMI at the current institution between 2001 and 2019.

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