Publications by authors named "C de-la-Camara"
The relationship between depression, particularly major depression (MD), as a risk factor for Alzheimer's disease (AD) is well established; however, its precise role remains contested. Findings from the fourth wave of the ZARADEMP longitudinal study provide further insights into the association between MD and AD risk. : This study aimed to examine the association between MD and incident AD, controlling for established risk factors.
View Article and Find Full Text PDFThis study aimed to explore the physiological dynamics of cognitive stress in patients with Major Depressive Disorder (MDD) and design a multiparametric model for objectively measuring severity of depression. Physiological signal recordings from 40 MDD patients and 40 healthy controls were collected in a baseline stage, in a stress-inducing stage using two cognitive tests, and in the recovery period. Several features were extracted from electrocardiography, photoplethysmography, electrodermal activity, respiration, and temperature.
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- The study examined the link between mild behavioral impairment (MBI) and dementia risk in older adults, following 4,803 individuals over 4.5 years.
- It found that in cognitively normal participants, decreased motivation—an MBI domain—was linked to a significantly increased risk of all-cause dementia.
- The researchers suggest decreased motivation might indicate a higher dementia risk, but more studies are needed to explore the relationship between MBI and various types of dementia.
Article Synopsis
- Poststroke cognitive impairment is common, but the exact changes in cognitive function following a first stroke compared to pre-stroke levels are not fully understood.
- The study aimed to track cognitive performance over time in stroke survivors versus individuals without strokes, using data from 14 international cohorts of older adults.
- Results showed that incident stroke led to a significant immediate drop in overall cognitive skills and accelerated decline in cognitive abilities over time.
Article Synopsis
- The study investigates how cardiometabolic multimorbidity (CMM) and depression affect cognitive function in older adults, aiming to understand their individual and combined impacts.
- It harmonizes data from 14 international cohort studies and utilizes various scales to assess CMM and depression among participants who did not have dementia at the start of the study.
- Findings include the analysis of over 30,000 older adults, revealing that both CMM and depression are linked to cognitive decline, with further validation through additional studies across different settings.