Publications by authors named "C de Roux Serratrice"

Faecal incontinence (FI) in the elderly is a common but underdiagnosed condition. It leads to social stigma and impacts patients' quality of life. The aetiology of FI is multifactorial.

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Objectives: This report aimed to describe mortality at 18 months in older survivors of the first wave of COVID-19.

Design: Observational cohort study.

Setting And Participants: Patients aged ≥65 years hospitalized for COVID-19 in the acute geriatric wards of 2 centers.

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Article Synopsis
  • Two COVID-19 outbreaks in Switzerland in 2020 led to changes in treatment approaches based on new medical evidence, with a study focusing on patient outcomes during these waves.
  • A total of 2,983 hospitalized patients were analyzed, finding similar in-hospital mortality rates between the first wave (16.3%) and the second wave (16.0%), but notable differences in ICU admissions and treatments used.
  • During the second wave, fewer patients were admitted to the ICU but had higher mortality rates; corticosteroids became the main treatment compared to previous use of medications like hydroxychloroquine, leading to a 25% reduction in mortality risk overall during the second wave.
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Mesalazine is often used as first-line therapy for ulcerative colitis. Several reports have pointed to systemic adverse reactions associated with this drug. Most have evoked a drug-induced hypersensitivity syndrome, while some have described lupus syndromes but with limited clinical and varied biological features.

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Platelet aggregation has been associated with COVID-19 pathogenesis. In older patients hospitalized for SARS-CoV-2 pneumonia, we aimed to investigate the association between aspirin use before admission and the risk of in-hospital all-cause mortality. We performed a retrospective international cohort study in five COVID-19 geriatric units in France and Switzerland.

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