Publications by authors named "C de Roquetaillade"
In patients with acute brain injury (ABI), optimizing cerebral perfusion parameters relies on multimodal monitoring. This include data from systemic monitoring-mean arterial pressure (MAP), arterial carbon dioxide tension (PaCO), arterial oxygen saturation (SaO), hemoglobin levels (Hb), and temperature-as well as neurological monitoring-intracranial pressure (ICP), cerebral perfusion pressure (CPP), and transcranial Doppler (TCD) velocities. We hypothesized that these parameters alone were not sufficient to assess the risk of cerebral ischemia.
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- Imported malaria is becoming a significant health issue in non-endemic countries, particularly due to increased global travel, prompting a study to explore cytokine profiles in affected individuals in France.
- The research involved 278 adults with Plasmodium falciparum malaria, classifying them into uncomplicated (UM) and severe malaria (SM), with findings showing a notable association between high IL-10 levels and both disease severity and higher parasitemia.
- The study revealed that many patients had undetectable cytokine levels at admission, indicating that routine cytokine testing may not be useful, but high IL-10 concentrations could be important for monitoring severe cases and potential infections.
Background: Effects of early mobilization are not well documented in patients with aneurysmal subarachnoid hemorrhage (aSAH). Only a few studies have investigated it through progressive mobilization protocols and suggested that it is safe and feasible. This study aimed to determine the impact of early out-of-bed mobilization (EOM) on 3-month functional outcome and cerebral vasospasm (CVS) occurrence in patients with aSAH.
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- Mid-regional pro-adrenomedullin (MR-proADM) levels are associated with mortality risk in COVID-19 patients, helping to differentiate between survivors and non-survivors.
- A comprehensive review of studies showed that survivors had significantly lower MR-proADM levels compared to non-survivors, with specific statistical differences indicating strong significance.
- The findings suggest that MR-proADM could be a valuable tool for assessing severity, guiding treatment decisions, and predicting patient outcomes; however, further large-scale studies are needed to confirm its diagnostic role.